LPHI publications since 2014

Team M. Lebrun / C. Braun-Breton

• Suarez C, Lentini G, Ramaswamy R, Maynadier M, Aquilini E, Berry-Sterkers L, Cipriano M, Chen AL, Bradley P, Striepen B, Boulanger MJ, Lebrun M (2019) A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites. Nat Commun. 10(1):4041. doi: 10.1038/s41467-019-11979-z.
• Semenovskaya K, Lévêque MF, Berry L, Bordat Y, Dubremetz JF, Lebrun M, Besteiro S (2019) TgZFP2 is a novel zinc finger protein involved in coordinating mitosis and budding in Toxoplasma. Cell Microbiol. e13120. doi: 10.1111/cmi.13120
• Berger O, Ortial S, Wein S, Denoyelle S, Bressolle F, Durand T, Escale R, Vial HJ, Vo-Hoang Y (2019) Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials. Bioorg Med Chem Lett. 29(16):2203-2207. doi: 10.1016/j.bmcl.2019.06.045
• Cheviet T, Lefebvre-Tournier I, Wein S, Peyrottes S (2019) Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues. J Med Chem. 62(18):8365-8391. doi: 10.1021/acs.jmedchem.9b00182
• Besteiro S (2019) The role of host autophagy machinery in controlling Toxoplasma infection. Virulence 10(1):438-447. doi: 10.1080/21505594.2018.1518102

Team JJ. Lopez-Rubio

• Vergnes B, Gazanion E, Mariac C, Du Manoir M, Sollelis L, Lopez-Rubio JJ, Sterkers Y, Bañuls AL (2019) A single amino acid substitution (H451Y) in Leishmania calcium-dependent kinase SCAMK confers high tolerance and resistance to antimony. J Antimicrob Chemother. 74(11):3231-3239. doi: 10.1093/jac/dkz334
• Lee MCS, Lindner SE, Lopez-Rubio JJ, Llinás M (2019) Cutting back malaria: CRISPR/Cas9 genome editing of Plasmodium. Brief Funct Genomics. pii: elz012. doi: 10.1093/bfgp/elz012

Team V. Molle

• Garai P, Berry L, Moussouni M, Bleves S, Blanc-Potard AB (2019) Killing from the inside: Intracellular role of T3SS in the fate of Pseudomonas aeruginosa within macrophages revealed by mgtC and oprF mutants. PLoS Pathog. 15(6):e1007812. doi: 10.1371/journal.ppat.1007812. 
• Moussouni M, Nogaret P, Garai P, Ize B, Vives E, Blanc-Potard AB (2019) Activity of a synthetic peptide targeting MgtC on Pseudomonas aeruginosa intramacrophage survival and biofilm formation. Front Cell Infect Microbiol, 9:84. doi: 10.3389/fcimb.2019.00084
• Virmani R, Sajid A, Singhal A, Gaur M, Joshi J, Bothra A, Garg R, Misra R, Singh VP, Molle V, Goel AK, Singh A, Kalia VC, Lee JK, Hasija Y, Arora G, Singh Y (2019) The Ser/Thr protein kinase PrkC imprints phenotypic memory in Bacillus anthracis spores by phosphorylating the glycolytic enzyme enolase. J Biol Chem. 294(22):8930-8941. doi: 10.1074/jbc.RA118.005424
• Brelle S, Martinez, E, Huc-Brandt S, Allombert J, Cantet F, Gannoun Zaki L, Letourneur F, Bonazzi, Molle V (2019) The Coxiella burnetii secreted protein kinase CstK influences vacuole development and interacts with the GTPase-activating protein TBC1D5. BioRxiv doi: 10.1101/611707

 
Team M. Vidal

• N. Bec, A. Bonhoure, L. Henry, L. Berry, C. Larroque, O. Coux, P-E. Stoebner and M. Vidal (2019) Proteasome 19S RP and translation preinitiation complexes are secreted within exosomes upon serum starvation. Traffic 20(7):516-536. doi: 10.1111/tra.12653. 
• Vidal M (2019) Exosomes: Revisiting their role as "garbage bags". Traffic 20(11):815-828. doi: 10.1111/tra.12687.

Team O. Radulescu / A. Parmeggiani

• Ana Zúñiga, Sarah Guiziou, Pauline Mayonove, Zachary Ben Meriem, Miguel Camacho, Violaine Moreau, Luca Ciandrini, Pascal Hersen, and Jerome Bonnet, Rational programming of history-dependent logic in cellular populations, bioRxiv doi: 10.1101/617209
• Y Rousset, L Ciandrini, N Kern (2019) Exclusion process subject to conformational size changes, arXiv 1902.03645x
• LD Fernandes, L Ciandrini, Driven transport on a flexible polymer with particle recycling: a model inspired by transcription and translation (2019) arXiv 1803.08110 
• Guilherme C.P. Innocentini, Fernando Antoneli, Arran Hodgkinson, Ovidiu Radulescu. Effective computational methods for hybrid stochastic gene networks. arXiv :1905.00235 (2019) https://arxiv.org/abs/1905.00235.
• M.Buffard, A.Naldi, O.Radulescu, P.Coopman, R.Larive, G.Freiss (2019) Network reconstruction and significant pathway extraction using phosphoproteomic data from cancer cells, Proteomics. e1800450. doi: 10.1002/pmic.201800450
• Russel Bradford, James H Davenport, Matthew England, Hassan Errami, Vladimir Gerdt, Dima Grigoriev, Charles Hoyt, M Kosta, Ovidiu Radulescu, Thomas Sturm, Andreas Weber (2019) Identifying the Parametric Occurrence of Multiple Steady States for some Biological Networks. Journal of Symbolic Computation, in press.
• Arran Hodgkinson, Laurent Le Cam, Dumitru Trucu, and Ovidiu Radulescu (2019) Spatio-Genetic and Phenotypic Modelling Elucidates Resistance and Re-Sensitisation to Treatment in Heterogeneous Melanoma, Journal of Theoretical Biology, 466:84-105. doi: 10.1016/j.jtbi.2018.11.037

Team G. Lutfalla

• Yatime L (2019) Structural analysis of S100A8 complex with zinc and calcium: a general protocol for the study of S100 proteins in the presence of divalent cations by X-ray crystallography. In C. Heizmann (eds.), Calcium-Binding Proteins of the EF-Hand Superfamily (pp. 417-435). Methods in Molecular Biology, vol. 1929, Humana Press, New York, NY. doi:10.1007/978-1-4939-9030-6_26

Team K. Kissa

• Travnickova J, Nhim S, Abdellaoui N, Djouad F, Nguyen-Chi M, Parmeggiani A and Kissa K (2019) Macrophage plasticity is Rac signalling and MMP9 dependant. BIORXIV/2019/614388. 2019 Apri.

Team G. Uzé

• Cauwels A., Van Lint S., Catteeuw D., Pang S., Paul F. Rogge E., Verhee A., Prinz M., Kley N., Uze G., Tavernier, J. (2019) Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice. J. Autoimmunity. 97: 70-76. 2019. doi: 10.1016/j.jaut.2018
• Lamure S, Carles C, Aquereburu Q, Quittet P, Tchernonog E, Paul F, Jourdan E, Waultier A, Defez C, Belhadj I, Sanhes L, Burcheri S, Donadio D, Exbrayat C, Saad A, Labourey JL, Baldi I, Cartron G, Fabbro-Peray P. (2019) Association of Occupational Pesticide Exposure With Immunochemotherapy Response and Survival Among Patients With Diffuse Large B-Cell Lymphoma. JAMA Netw Open. 2(4):e192093 5. doi: 10.1001/jamanetworkopen.2019.2093.
• Gourzones C, Bellanger C, Lamure S, Gadacha OK, De Paco EG, Vincent L, Cartron G, Klein B, Moreaux J.(2019) Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells. Cancers (Basel). 11(4). pii: E439. doi: 10.3390/cancers11040439
• Jamois C, Gibiansky E, Gibiansky L, Buchheit V, Sahin D, Cartron G, Marcus R, Hiddemann W, Seymour JF, Strefford JC, Hargreaves CE, Meneses-Lorente G, Frey N, Fingerle-Rowson G. (2019) Role of obinutuzumab exposure on clinical outcome of follicular lymphoma treated with first-line immunochemotherapy. Br J Clin Pharmacol. 85(7):1495-1506. doi: 10.1111/bcp.13920.

Team M. Lebrun / C. Braun-Breton

• Ma, S., Cahalan, S., LaMonte, G., Grubaugh, N. D., Zeng, W., Murthy, S. E., Paytas, E., Gamini, R., Lukacs, V., Whitwam, T., Loud, M., Lohia, R., Berry, L., Khan, S. M., Janse, C. J., Bandell, M., Schmedt, C., Wengelnik, K., Su, A. I., Honore, E., Winzeler, E. A., Andersen, K. G., and Patapoutian, A. (2018) Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection. Cell 173, 443-455 e412
• Andreadaki, M., Hanssen, E., Deligianni, E., Claudet, C., Wengelnik, K., Mollard, V., McFadden, G. I., Abkarian, M., Braun-Breton, C., and Siden-Kiamos, I. (2018) Sequential Membrane Rupture and Vesiculation during Plasmodium berghei Gametocyte Egress from the Red Blood Cell. Sci Rep 8, 3543
• Wein, S., Ghezal, S., Bure, C., Maynadier, M., Perigaud, C., Vial, H. J., Lefebvre-Tournier, I., Wengelnik, K., and Cerdan, R. (2018) Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite. J Lipid Res., 58, 1461-1471.
• Guca, E., Nagy, G. N., Hajdu, F., Marton, L., Izrael, R., Hoh, F., Yang, Y., Vial, H., Vertessy, B. G., Guichou, J. F., and Cerdan, R. (2018) Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep., 8, 11215
• Nguyen HM, Liu S, Daher W, Tan F, Besteiro S. (2018) Characterisation of two Toxoplasma PROPPINs homologous to Atg18/WIPI suggests they have evolved distinct specialised functions. PLoS One. Apr 16;13(4):e0195921.
• Berry L, Chen CT, Francia ME, Guerin A, Graindorge A, Saliou JM, Grandmougin M, Wein S, Bechara C, Morlon-Guyot J, Bordat Y, Gubbels MJ, Lebrun M, Dubremetz JF, Daher W. (2018) Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny. Cell Mol Life Sci. Jul 26.
• Morlon-Guyot J, El Hajj H, Martin K, Fois A, Carrillo A, Berry L, Burchmore R, Meissner M, Lebrun M, Daher W. (2018) A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis. Cellular Microbiology. 17:e12870.
• Morlon-Guyot J, Berry L, Sauquet I, Singh Pall G, El Hajj H, Meissner M, Daher W. (2018) Conditional knockdown of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii. Mol Biochem Parasitol. 2018 Jul;223:19-30. doi:10.1016/j.molbiopara.2018.06.003.

Team V. Molle

• Moussaed M, Huc-Brandt S, Cubedo N, Silhol M, Murat S, Lebart MC, Kovacs G, Verdier JM, Trousse F, Rossel M, Marcilhac A. Regenerating islet-derived 1α (REG-1α) protein increases tau phosphorylation in cell and animal models of tauopathies. Neurobiol Dis. 2018 Nov;119:136-148.
• Eisenbeis J, Saffarzadeh M, Peisker H, Jung P, Thewes N, Preissner KT,Herrmann M, Molle V, Geisbrecht BV, Jacobs K, Bischoff M. The Staphylococcus aureus Extracellular Adherence Protein Eap Is a DNA Binding Protein Capable of Blocking Neutrophil Extracellular Trap Formation. Front Cell Infect Microbiol.2018 Jul 9;8:235.
• Guzzo M, Murray SM, Martineau E, Lhospice S, Baronian G, My L, Zhang Y,Espinosa L, Vincentelli R, Bratton BP, Shaevitz JW, Molle V, Howard M, Mignot T. A gated relaxation oscillator mediated by FrzX controls morphogenetic movementsin Myxococcus xanthus. Nat Microbiol. 2018 Aug;3(8):948-959.
• Gannoun-Zaki L, Pätzold L, Huc-Brandt S, Baronian G, Elhawy MI, Gaupp R,Martin M, Blanc-Potard AB, Letourneur F, Bischoff M, Molle V. PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with coronin-1A during infection. J Biol Chem. 2018 Oct5;293(40):15569-15580.

Team M. Vidal

• L. Blanc and M. Vidal (2018) New Insights into the function of Rab GTPases in the context of exosomal secretion. Small GTPases. 9 (1-2) : 95-106.

Team O. Radulescu / A. Parmeggiani

• Hodgkinson A, Uzé G, Radulescu O, Trucu D. Signal Propagation in Sensing and Reciprocating Cellular Systems with Spatial and Structural Heterogeneity. Bull Math Biol. 80:1900-1936. 2018.
• M Bellec, O Radulescu, M Lagha, Remembering the past: mitotic bookmarking in a developing embryo. Current Opinion in Systems Biology (2018) 11, 41-49.
• AW F. Boulier, F. Fages, O. Radulescu, S. Samal, A. Schuppert, W. Seiler, T, The SYMBIONT Project: Symbolic Methods for Biological Networks, F1000Research 7, 1341. ACM Communications in Computer Algebra 2019, 52:67-70
• J Dufourt, A Trullo, J Hunter, C Fernandez, J Lazaro, M Dejean, L Morales, K N Schulz, C.Favard, M.M. Harrison, O. Radulescu, M. Lagha. Temporal Control of Transcription by Zelda in living Drosophila embryos, Nature Communications, 2018, 9 (1): 5194.
• A Hodgkinson, O Radulescu. An in silico spatio-structural mathematical model for plastic drug resistance in heterogeneous melanoma subpopulations. Cancer Research (2018) 78 (10), 69-70
• G Innocentini, A Hodgkinson, O Radulescu Time Dependent Stochastic mRNA and Protein Synthesis in Piecewise-deterministic Models of Gene Networks. Frontiers in Physics. (2018) 6, 46
• Vigneron S, Sundermann L, Labbé JC, Pintard L, Radulescu O, Castro A, Lorca T. Cyclin A-cdk1 Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry. Dev Cell. (2018) Jun 4;45(5):637-650.e7.
• Walter, J.-C., Walliser, N.-O., David, G., Dorignac, J., Geniet, F., Palmeri, J., Parmeggiani, A., Wingreen, N. s. and Broedersz, C. P. "Looping and clustering model for the organization of protein-DNA complexes on the bacterial genome", New Journal of Physics 20, 14 pages, 7 figures, 2018, pp. 035002.
• Debaugny, R., Sanchez, A., Rech, J., Labourdette, D., Dorignac, J., Geniet, F., Palmeri, J., Parmeggiani, A., Boudsocq, F., Le Berre, V., Walter, J.-C. and Bouet, J.-y. "A conserved mechanism drives partition complex assembly on bacterial chromosomes and plasmids", Molecular Systems Biology 14(11), 2018, pp. e8516.
• Szavits-Nossan, Juraj, Romano, M Carmen, Ciandrini, Luca. Power series solution of the inhomogeneous exclusion process. Physical Review E (2018) 97: 052139.
• Szavits-Nossan, Juraj, Ciandrini, Luca and Romano, M Carmen. Deciphering mRNA sequence determinants of protein production rate. Physical review letters (2018) 12: 128101.
• A Hodgkinson. A Novel Cellular Automata Modelling Framework for Micro-environmental Interaction and Coinvasion. In: G Mauri, S El Yacoubi, A Dennunzio, K Nishinari, L Manzoni. Lecture Notes in Computer Science: Proceedings of the 13th International Conference on Cellular Automata for Research and Industry (2018) p30-41.

Team G. Lutfalla

• Phan QT, Sipka T, Gonzalez C, Levraud JP, Lutfalla G, Nguyen-Chi M (2018) Neutrophils use superoxide to control bacterial infection at a distance. Plos Pathog 14:e1007157. doi:10.1371/journal.ppat.1007157
• Yatime L, Merle NS, Hansen AG, Friis NA, Østergaard JA, Bjerre M, Roumenina LT, Thiel S, Kristensen P, Andersen GR (2018) A single-domain antibody targeting complement component C5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the C-terminal domain of the Staphylococcus aureus SSL7 protein. Front Immunol 9:2822. doi:10.3389/fimmu.2018.02822

Team K. Kissa

• Poullet N, Golushko I, Lorman V, Travnickova J, Rochal S, Parmeggiani A and Kissa K. Mechanical instabilities of aorta drive blood stem cell production: a live study. BIORXIV/2018/509190. 2018 Dec.

Team G. Uzé

• Hodgkinson A, Uzé G, Radulescu O, Trucu D. Signal Propagation in Sensing and Reciprocating Cellular Systems with Spatial and Structural Heterogeneity. Bull Math Biol. 80:1900-1936. 2018.
• Cauwels A, Van Lint S, Paul F, Garcin G, De Koker S, Van Parys A, Wueest T, Gerlo S, Van der Heyden J, Bordat Y, Catteeuw D, Rogge E, Verhee A, Vandekerckhove B, Kley N, Uzé G, Tavernier J. Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments. Cancer Res. 78:463-474. 2018.
• Houot R, Cartron G, Bijou F, de Guibert S, Salles GA, Fruchart C, Bouabdallah K, Maerevoet M, Feugier P, Le Gouill S, Tilly H, Casasnovas RO, Moluçon-Chabrot C, Van Den Neste E, Zachee P, Andre M, Bonnet C, Haioun C, Van Hoof A, Van Eygen K, Molina L, Nicolas-Virelizier E, Ruminy P, Morschhauser F. (2019) Obinutuzumab plus Lenalidomide (GALEN) for the treatment of relapse/refractory aggressive lymphoma: a phase II LYSA study. Leukemia. 33(3):776-780.
• Castillo JJ, Guerrero-Garcia T, Baldini F, Tchernonog E, Cartron G, Ninkovic S, Cwynarski K, Dierickx D, Tousseyn T, Lansigan F, Linnik Y, Mogollon R, Navarro JT, Olszewski AJ, Reagan JL, Fedele P, Gilbertson M, Grigoriadis G, Bibas M. (2019) Bortezomib plus EPOCH is effective as frontline treatment in patients with plasmablastic lymphoma. Br J Haematol. 184(4):679-682.
• Herviou L, Kassambara A, Boireau S, Robert N, Requirand G, Müller-Tidow C, Vincent L, Seckinger A, Goldschmidt H, Cartron G, Hose D, Cavalli G, Moreaux J. (2018) PRC2 targeting is a therapeutic strategy for EZ score defined highrisk multiple myeloma patients and overcome resistance to IMiDs. Clin Epigenetics. 10(1):121.
• Morschhauser F, Fowler NH, Feugier P, Bouabdallah R, Tilly H, Palomba ML, Fruchart C, Libby EN, Casasnovas RO, Flinn IW, Haioun C, Maisonneuve H, Ysebaert L, Bartlett NL, Bouabdallah K, Brice P, Ribrag V, Daguindau N, Le Gouill S, Pica GM, Martin Garcia-Sancho A, López-Guillermo A, Larouche JF, Ando K, Gomes da Silva M, André M, Zachée P, Sehn LH, Tobinai K, Cartron G, Liu D, Wang J, Xerri L, Salles GA; RELEVANCE Trial Investigators. (2018) Rituximab plus Lenalidomide in Advanced Untreated Follicular Lymphoma. N Engl J Med. 379(10):934-947.
• Sanchez-Martinez D, Allende-Vega N, Orecchioni S, Talarico G, Cornillon A, Vo DN, Rene C, Lu ZY, Krzywinska E, Anel A, Galvez EM, Pardo J, Robert B, Martineau P, Hicheri Y, Bertolini F, Cartron G, Villalba M. (2018) Expansion of allogeneic NK cells with efficient antibody-dependent cell cytotoxicity against multiple tumors. Theranostics. 8(14):3856-3869.
• Federico M, Caballero Barrigón MD, Marcheselli L, Tarantino V, Manni M, Sarkozy C, Alonso-Álvarez S, Wondergem M, Cartron G, Lopez-Guillermo A, Issa D, Morschhauser F, Alcoceba M, Kimby E, Rusconi C, Chamuleau M, Holte H,
• Lockmer S, Montoto S, Gomes da Silva M, Aurer I, Zucca E, Paszkiewicz-Kozik E, Minoia C, Skrypets T, Blaker YN, Salles G, Coiffier B; Aristotle Consortium. (2018) Rituximab and the risk of transformation of follicular lymphoma: a retrospective pooled analysis. Lancet Haematol. 5(8):e359-e367
• Morschhauser F, Salles G, Le Gouill S, Tilly H, Thieblemont C, Bouabdallah K, Fabiani B, Ménard C, Tarte K, Cartron G, Houot R. (2018) An open-label phase 1b study of obinutuzumab plus lenalidomide in relapsed/refractory follicular B-cell lymphoma. Blood. 132(14):1486-1494.
• Orvain C, Da Costa L, Van Wijk R, Pissard S, Picard V, Mansour-Hendili L, Cunat S, Giansily-Blaizot M, Cartron G, Schved JF, Aguilar-Martinez P. (2018) Inherited or acquired modifiers of iron status may dramatically affect the phenotype in dehydrated hereditary stomatocytosis. Eur J Haematol. 101(4):566-569.
• Khan AUH, Allende-Vega N, Gitenay D, Garaude J, Vo DN, Belkhala S, Gerbal-Chaloin S, Gondeau C, Daujat-Chavanieu M, Delettre C, Orecchioni S, Talarico G, Bertolini F, Anel A, Cuezva JM, Enriquez JA, Cartron G, Lecellier CH, Hernandez J, Villalba M. (2018) Mitochondrial Complex I activity signals antioxidant response through ERK5. Sci Rep. 8(1):7420
• Szablewski V, Bret C, Kassambara A, Devin J, Cartron G, Costes-Martineau V, Moreaux J. (2018) An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy. Oncotarget. 9(27):19079-19099.
• Al Tabaa Y, Tchernonog E, Faurie P, Cottereau AS, Monjanel H, Bonnet A, Le Gouill S, Gyan E, Ghesquieres H, Mariano-Goulart D, Cartron G. (2018) Post-treatment positron emission tomography-computed tomography is highly predictive of outcome in Plasmablastic lymphoma. Eur J Nucl Med Mol Imaging. 45(10):1705-1709.
• Seymour JF, Kipps TJ, Eichhorst B, Hillmen P, D'Rozario J, Assouline S, Owen C, Gerecitano J, Robak T, De la Serna J, Jaeger U, Cartron G, Montillo M,  Humerickhouse R, Punnoose EA, Li Y, Boyer M, Humphrey K, Mobasher M, Kater AP. (2018) Venetoclax-Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia. N Engl J Med. 378(12):1107-1120.
• Lamure S, Delage J, Vincent L, Fegueux N, Zhao-Yang L, Cartron G, Ceballos P, De Vos J. (2018) Infusion of in vivo expanded cord blood lymphocytes: A new strategy to control residual disease? Curr Res Transl Med. 66(3):91-93.
• Cartron G, Letestu R, Dartigeas C, Tout M, Mahé B, Gagez AL, Ferrant E, Guiu B, Villemagne B, Letuan P, Aurran T, Orsini-Piocelle F, Banos A, Feugier P, Leblond V, de Guibert S, Tournilhac O, Dupuis J, Delmer A, Rouillé V, Ternant D, Leprêtre S. (2018) Increased rituximab exposure does not improve response and outcome of patients with chronic lymphocytic leukemia after fludarabine, cyclophosphamide, rituximab. A French Innovative Leukemia Organization (FILO) study. Haematologica. 103(8):e356-e359.
• Bruyer A, Maes K, Herviou L, Kassambara A, Seckinger A, Cartron G, Rème T, Robert N, Requirand G, Boireau S, Müller-Tidow C, Veyrune JL, Vincent L, Bouhya S, Goldschmidt H, Vanderkerken K, Hose D, Klein B, De Bruyne E, Moreaux J. (2018) DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells. Br J Cancer. 2018 Apr;118(8):1062-1073.
• Baik H, Boulanger M, Hosseini M, Kowalczyk J, Zaghdoudi S, Salem T, Sarry JE, Hicheri Y, Cartron G, Piechaczyk M, Bossis G. (2018) Targeting the SUMO Pathway Primes All-trans Retinoic Acid-Induced Differentiation of Nonpromyelocytic Acute Myeloid Leukemias. Cancer Res. 2018 May 15;78(10):2601-2613.
• Lodé L, Ménard A, Flet L, Richebourg S, Loirat M, Eveillard M, Le Bris Y, Godon C, Theisen O, Gagez AL, Cartron G, Commes-Maerten T, Villemagne B, Luycx O, Godmer P, Pellat-Deceunynck C, Soussi T, Béné MC, Delaunay J, Peterlin P. (2018) Emergence and evolution of TP53 mutations are key features of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide. Haematologica. 103(4):e143-e146.
• Fossard G, Broussais F, Coelho I, Bailly S, Nicolas-Virelizier E, Toussaint E, Lancesseur C, Le Bras F, Willems E, Tchernonog E, Chalopin T, Delarue R, Gressin R, Chauchet A, Gyan E, Cartron G, Bonnet C, Haioun C, Damaj G, Gaulard P, Fornecker L, Ghesquières H, Tournilhac O, da Silva MG, Bouabdallah R, Salles G, Bachy E. (2018) Role of up-front autologous stem-cell transplantation in peripheral T-cell lymphoma for patients in response after induction: an analysis of patients from LYSA centers. Ann Oncol. 29(3):715-723.
• Lamy T, Damaj G, Soubeyran P, Gyan E, Cartron G, Bouabdallah K, Gressin R, Cornillon J, Banos A, Le Du K, Benchalal M, Moles MP, Le Gouill S, Fleury J, Godmer P, Maisonneuve H, Deconinck E, Houot R, Laribi K, Marolleau JP, Tournilhac O, Branger B, Devillers A, Vuillez JP, Fest T, Colombat P, Costes V, Szablewski V, Béné MC, Delwail V; LYSA Group. (2018) R-CHOP 14 with or without radiotherapy in nonbulky limited-stage diffuse large B-cell lymphoma. Blood. 131(2):174-181.

Team M. Lebrun / C. Braun-Breton

• Besteiro S. (2017) Autophagy in apicomplexan parasites. Curr Opin Microbiol. 40:14-20 Pubmed
• Nguyen HM, Berry L, Sullivan WJ Jr, Besteiro S. (2017) Autophagy participates in the unfolded protein response in Toxoplasma gondii. FEMS Microbiol Lett. 15;364(15). Pubmed
• Di Cristina M, Dou Z, Lunghi M, Kannan G, Huynh MH, McGovern OL, Schultz TL, Schultz AJ, Miller AJ, Hayes BM, van der Linden W, Emiliani C, Bogyo M, Besteiro S, Coppens I, Carruthers VB. (2017) Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection. Nat Microbiol. Jun 19;2:17096. Pubmed
• Nguyen HM, El Hajj H, El Hajj R, Tawil N, Berry L, Lebrun M, Bordat Y, Besteiro S. (2017)  Toxoplasma gondii autophagy-related protein ATG9 is crucial for the survival of parasites in their host.  Cell Microbiol. In press. Pubmed
• Latré de Laté P, Pineda M, Harnett M, Harnett W, Besteiro S, Langsley G. (2017) Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells. Biomed J. 40(1):23-30. Pubmed
• Harnett MM, Pineda MA, Latré de Laté P, Eason RJ, Besteiro S, Harnett W, Langsley G. (2017). From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home. Biomed J. 40(1):9-22. Pubmed
• Wein S, Taudon N, Maynadier M, Tran Van Ba C, Margout D, Bordat Y, Fraisse L, Wengelnik K, Cerdan R, Bressolle-Gomeni F, Vial HJ. High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death. Antimicrob Agents Chemother. 2017 Jul  25;61(8). pii: e00352-17. doi: 10.1128/AAC.00352-17.
• Francisco Hilario F, Traoré M, Zwick V, Berry L, Simões-Pires C, Cuendet M, Fantozzi N, Pereira de Freitas R, Maynadier  M, Wein S, Vial H, Wong, YS. Synthesis of an uncharged tetra-cyclopeptide acting as transmembrane carrier: enhanced cellular and nuclear uptake. Organic Letters, 2017, 19(3):612-615.
• Traoré M. D. M.,  Zwick V.,  Simões-Pires C. A., Nurisso A. ,  Issa M.,  Cuendet M., Maynadier M. , Wein S. , Vial H. , Jamet  H. and  Wong Y-S. Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6. ACS Omega, 2017, 2 (4), pp 1550–1562 , DOI: 10.1021/acsomega.6b00481
• Nguyen HM, Berry L, Sullivan WJ Jr, Besteiro S. (2017) Autophagy participates in the unfolded protein response in Toxoplasma gondii. FEMS Microbiol Lett. 15;364(15). Pubmed
• Di Cristina M, Dou Z, Lunghi M, Kannan G, Huynh MH, McGovern OL, Schultz TL, Schultz AJ, Miller AJ, Hayes BM, van der Linden W, Emiliani C, Bogyo M, Besteiro S, Coppens I, Carruthers VB. (2017) Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection. Nat Microbiol. Jun 19;2:17096. Pubmed
• Vasiliauskaite-Brooks I, Sounier R, Rochaix P, Bellot G, Fortier M, Hoh F, De Colibus L, Bechara C, Saied EM, Arenz C, Leyrat C, Granier S. Structural insights into adiponectin receptors suggest ceramidase activity. Nature. 2017 Apr 6;544(7648):120-123.
• Pegoraro, S., Duffey, M., Otto, T. D., Wang, Y., Rosemann, R., Baumgartner, R., Fehler, S. K., Lucantoni, L., Avery, V. M., Moreno-Sabater, A., Mazier, D., Vial, H. J., Strobl, S., Sanchez, C. P., and Lanzer, M. (2017) SC83288 is a clinical development candidate for the treatment of severe malaria. Nat Commun 8, 14193
• Bushell, E., Gomes, A. R., Sanderson, T., Anar, B., Girling, G., Herd, C., Metcalf, T., Modrzynska, K., Schwach, F., Martin, R. E., Mather, M. W., McFadden, G. I., Parts, L., Rutledge, G. G., Vaidya, A. B., Wengelnik, K., Rayner, J. C., and Billker, O. (2017) Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Cell 170, 260-272 e268
• Guerin A, El Hajj H, Penarete-Vargas D, Besteiro S, Lebrun M. (2017)RON4(L1) is a new member of the moving junction complex in Toxoplasma gondii. Sci Rep. Dec 20;7(1):17907.
• Leveque MF, Berry L, Yamaryo-Botte Y, Nguyen HM, Galera M, Botte CY, Besteiro S. (2017) TgPL2, a patatinlike phospholipase domain-containing protein, is involved in the maintenance of apicoplast lipids homeostasis in Toxoplasma. Mol Microbiol. Jul;105(1):158-174. doi: 10.1111/mmi.13694. Epub 2017 May 3. PubMed PMID:28419631.
• Lentini G, El Hajj H, Papoin J, Fall G, Pfaff AW, Tawil N, Braun-Breton C, Lebrun M. (2017) Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice. PLoS One. Dec 15;12(12):e0189556.
• Guerin A, Corrales RM, Parker ML, Lamarque MH, Jacot D, El Hajj H, Soldati-Favre D, Boulanger MJ, Lebrun M. (2017) Efficient invasion by Toxoplasma depends on the subversion of host protein networks. Nat Microbiol. Oct;2(10):1358-1366.
• Miliu A, Lebrun M, Braun-Breton C, Lamarque MH. (2017) Shelph2, a bacterial-like phosphatase of the malaria parasite Plasmodium falciparum, is dispensable during asexual blood stage. PLoS One. Oct 26;12(10):e0187073.

Team V. Molle

• Rosas Olvera M, Vives E, Molle V, Blanc-Potard AB, Gannoun-Zaki L. Endogenous and Exogenous KdpF Peptide Increases Susceptibility of Mycobacterium bovis BCG to Nitrosative Stress and Reduces Intramacrophage Replication. Front Cell Infect Microbiol. 2017 Apr 6;7:115.
• Barlocher K, Hutter CAJ, Swart AL, Steiner B, Welin A, Hohl M, Letourneur F,Seeger MA, Hilbi H. Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5. Nat Commun. 2017 Nov 16;8(1):1543.
• Bischoff M, Wonnenberg B, Nippe N, Nyffenegger-Jann NJ, Voss M, Beisswenger C,Sunderkotter C, Molle V, Dinh QT, Lammert F, Bals R, Herrmann M, Somerville GA,Tschernig T, Gaupp R. CcpA Affects Infectivity of Staphylococcus aureus in a Hyperglycemic Environment. Front Cell Infect Microbiol. 2017 May 9;7:172.
• Arora G, Sajid A, Virmani R, Singhal A, Kumar CMS, Dhasmana N, Khanna T, Maji A, Misra R, Molle V, Becher D, Gerth U, Mande SC, Singh Y. Ser/Thr protein kinase PrkC-mediated regulation of GroEL is critical for biofilm formation in Bacillusanthracis. NPJ Biofilms Microbiomes. 2017 Mar 7;3:7.
• Shaw DJ, Robb K, Vetter BV, Tong M, Molle V, Hunt NT, Hoskisson PA. Disruptionof key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability. Sci Rep. 2017 Jul 5;7(1):4714.
• Moine A, Espinosa L, Martineau E, Yaikhomba M, Jazleena PJ, Byrne D, BiondiEG, Notomista E, Brilli M, Molle V, Gayathri P, Mignot T, Mauriello EMF. The nucleoid as a scaffold for the assembly of bacterial signaling complexes. PLoSGenet. 2017 Nov 21;13(11):e1007103.

Team M. Vidal

• A. Bonhoure, A. Vallentin, M. Martin, A. Senff-Ribeiro, R. Amson, A. Telerman and M. Vidal (2017) Acetylation of Translationally Controlled Tumor Protein promotes its degradation through Chaperone-Mediated Autophagy. Eur. J. Cell Biol. 96: 83-98.

Team O. Radulescu / A. Parmeggiani

• S Vakulenko, O Radulescu, I Morozov, A Weber. Centralized Networks to Generate Human Body Motions. Sensors 2017, 17 (12): 2907.
• E Kim, LM Tenkes, R Hollerbach, O Radulescu. Far-from-equilibrium time evolution between two gamma distributions. Entropy 2017, 19 (10): 511.
• A.Kozulic-Pirher, K Tanatale, F Muller, M Robert, C Zimmer, J Andrau, E Margeat, A L’Hostis, O Radulescu, E Bertrand, E Basyuk. A real time, single molecule view of transcription in living human cells. FEBS Journal 2017, 284:169.
• Mounia Lagha, Teresa Ferraro, Jeremy Dufourt, Ovidiu Radulescu, Matilde Mantovani. Transcriptional Memory in the Drosophila Embryo. Mechanisms of Development 145 (2017) S137.
• Satya Swarup Samal, Ovidiu Radulescu, Andreas Weber, Holger Frohlich. Linking metabolic network features to phenotypes using sparse group lasso. Bioinformatics 2017, 33 (21): 3445:3453.
• A.Naldi, R.M.Larive, U.Czerwinska, S.Urbach, P.Montcourrier,C.Roy, J.Solassol, G.Freiss, P.J.Coopman and O.Radulescu. Reconstruction and Signal Propagation Analysis of the Syk Signaling Network in Breast Cancer Cells.PLOS Computational Biology (2017) 13: e1005432.
• Walter, J.-C., Dorignac, J., Lorman, V., Rech, J., Bouet, J.-y., Nollmann, M., Palmeri, J., Parmeggiani, A. and Geniet, F. "Surfing on protein waves: proteophoresis as a mechanism for bacterial genome partitioning", Physical Review Letters 119(2), 6 pages, 3 figures, 2017, pp. 028101.
• Fernandes, Lucas D, De Moura, Alessandro PS and Ciandrini, Luca. Gene length as a regulator for ribosome recruitment and protein synthesis: theoretical insights. Scientific reports (2017) 7 : 17409

Team G. Lutfalla

• Morris EA, Bodin S, Delaval B, Comunale F, Georget V, Costa ML, Lutfalla G,  Gauthier-Rouvière C (2017) Flotillins control zebrafish epiboly through their role in cadherin-mediated cell-cell adhesion. Biol Cell 109:210-221. doi:10.1111/boc.201700001
• Nguyen-Chi M, Laplace-Builhé B, Travnickova J, Luz-Crawford P, Tejedor G, Lutfalla G, Kissa K, Jorgensen C, Djouad F (2017). TNF signaling and macrophages govern fin regeneration in zebrafish larvae. Cell Death Dis 8:e2979. doi:10.1038/cddis.2017.374
• Yatime L (2017) A cystein-dependent activation mechanism for the pro-inflammatory ligands of RAGE? Med Sci 33, 351-354. doi:10.1051/medsci/20173303026

Team G. Uzé

• Cauwels, A., Van Lint, S., Garcin, G., Bultinck, J., Paul, F., Gerlo, S., Van der Heyden, J., Bordat, Y., Catteeuw, D., De Cauwer, L., Rogge, E., Verhee, A., Uze, G. & Tavernier, J. A safe and highly efficient tumortargeted type I interferon immunotherapy depends on the tumor microenvironment. Oncoimmunology. 2017 Nov 27;7(3):e1398876.
• Vo DN, Alexia C, Allende-Vega N, Morschhauser F, Houot R, Menard C, Tarte K, Cartron G, Villalba M. (2017) NK cell activation and recovery of NK cell subsets in lymphoma patients after obinutuzumab and lenalidomide treatment. Oncoimmunology. 7(4):e1409322.
• Hernandez J, Daujat-Chavanieu M, Allende-Vega N, Gonzalez MV. (2017) Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status. Oncotarget. 9(1):1114-1129.
• P, Casasnovas O, Zerazhi H, Haioun C, Maisonneuve H, Houot R, Jardin F, Van Den Neste E, Tournilhac O, Le Du K, Morschhauser F, Cartron G, Fornecker LM, Canioni D, Callanan M, Bene MC, Salles G, Tilly H, Lamy T, Gressin R, Hermine O; LYSA Group. (2017) Rituximab after Autologous Stem-Cell Transplantation in Mantle-Cell Lymphoma. N Engl J Med. 377(13):1250-1260.
• Tudesq JJ, Vincent L, Lebrun J, Hicheri Y, Gabellier L, Busetto T, Merle C, Fegueux N, Ceballos P, Quittet P, Navarro R, Hillaire-Buys D, Cartron G. (2017) Cytomegalovirus Infection With Retinitis After Brentuximab Vedotin Treatment for CD30+ Lymphoma. Open Forum Infect Dis. 4(2):ofx091.
• Ben Bouallegue F, Tabaa YA, Kafrouni M, Cartron G, Vauchot F, Mariano-Goulart D. (2017) Association between textural and morphological tumor indices on baseline PET-CT and early metabolic response on interim PET-CT in bulky malignant lymphomas. Med Phys. 44(9):4608-4619.
• Xerri L, Huet S, Venstrom JM, Szafer-Glusman E, Fabiani B, Canioni D, Chassagne-Clement C, Dartigues-Cuilleres P, Charlotte F, Laurent C, Gelas-Dore B, Bolen CR, Punnoose E, Bouabdallah R, Brice P, Morschhauser F, Cartron G, Olive D, Salles G; a LYSA study. (2017) Rituximab treatment circumvents the prognostic impact of tumor-infiltrating T-cells in follicular lymphoma patients. Hum Pathol. 64:128-136.
• Long-term follow-up of patients with CLL treated with the selective Bruton's tyrosine kinase inhibitor ONO/GS-4059. Blood. 2017 May 18;129(20):2808-2810.
• Tout M, Casasnovas O, Meignan M, Lamy T, Morschhauser F, Salles G, Gyan E, Haioun C, Mercier M, Feugier P, Boussetta S, Paintaud G, Ternant D, Cartron G. (2017) Rituximab exposure is influenced by baseline metabolic tumor volume and predicts outcome of DLBCL patients: a Lymphoma Study Association report. Blood. 129(19):2616-2623.
• Gagez AL, Duroux-Richard I, Lepretre S, Orsini-Piocelle F, Letestu R, De Guibert S, Tuaillon E, Leblond V, Khalifa O, Gouilleux-Gruart V, Banos A, Tournilhac O, Dupuis J, Jorgensen C, Cartron G, Apparailly F. (2017) miR-125b and miR-532-3p predict the efficiency of rituximab-mediated lymphodepletion in chronic lymphocytic leukemia patients. A French Innovative Leukemia Organization study. Haematologica. 102(4):746-754.
• Tchernonog E, Faurie P, Coppo P, Monjanel H, Bonnet A, Algarte Genin M, Mercier M, Dupuis J, Bijou F, Herbaux C, Delmer A, Fabiani B, Besson C, Le Gouill S, Gyan E, Laurent C, Ghesquieres H, Cartron G. (2017) Clinical characteristics and prognostic factors of plasmablastic lymphoma patients: analysis of 135 patients from the LYSA group. Ann Oncol. 28(4):843-848.
• Meunier G, Ysebaert L, Nguyen-Thi PL, Lepretre S, Quinquenel A, Dupuis J, Lemal R, Aurran T, Tomowiak C, Cymbalista F, Dilhuydy MS, Brion A, Morel P, Cazin B, Leblond V, Cartron G, Re D, Bene MC, Michallet AS, Feugier (2017) First-line therapy for chronic lymphocytic leukemia in patients older than 79 years is feasible and achieves good results: A FILO retrospective study. Hematol Oncol. 35(4):671-678.
• Tout M, Gagez AL, Lepretre S, Gouilleux-Gruart V, Azzopardi N, Delmer A, Mercier M, Ysebaert L, Laribi K, Gonzalez H, Paintaud G, Cartron G, Ternant D. (2017) Influence of FCGR3A-158V/F Genotype and Baseline CD20 Antigen Count on Target-Mediated Elimination of Rituximab in Patients with Chronic Lymphocytic Leukemia: A Study of FILO Group. Clin Pharmacokinet. 56(6):635-647.

Team M. Lebrun / C. Braun-Breton

• Nguyen HM, El Hajj H, El Hajj R, Tawil N, Berry L, Lebrun M, Bordat Y, Besteiro S. Toxoplasma gondii autophagy-related protein ATG9 is crucial for the survival of parasites in their host. Cell Microbiol. 2016 Dec 19.
• Latré de Laté P, Pineda M, Harnett M, Harnett W, Besteiro S, Langsley G. (2017) Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells. Biomed J. 40(1):23-30. Pubmed
• Harnett MM, Pineda MA, Latré de Laté P, Eason RJ, Besteiro S, Harnett W, Langsley G. (2017). From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home. Biomed J. 40(1):9-22. Pubmed
• Berry L, Chen CT, Reininger L, Carvalho TG, El Hajj H, Morlon-Guyot J, Bordat Y, Lebrun M, Gubbels MJ, Doerig C, Daher W. The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence. Cell Microbiol. 2016 Aug;18(8):1106-20.
• Lévêque MF, Nguyen HM, Besteiro S. Repurposing of conserved autophagy-related protein ATG8 in a divergent eukaryote. Commun Integr Biol. 2016 Jul 1;9(4):e1197447.
• Lévêque MF, Berry L, Besteiro S. An evolutionarily conserved SSNA1/DIP13 homologue is a component of both basal and apical complexes of Toxoplasma gondii. Sci Rep. 2016 Jun 21;6:27809.
• Daher W, Morlon-Guyot J, Alayi TD, Tomavo S, Wengelnik K, Lebrun M. Identification of Toxoplasma TgPH1, a pleckstrin homology domain-containing protein that binds to the phosphoinositide PI(3,5)P2. Mol Biochem Parasitol. 2016 May;207(1):39-44.
• Braun-Breton C, Abkarian M. Red Blood Cell Spectrin Skeleton in the Spotlight. Trends Parasitol. 2016 Feb;32(2):90-2.
• Parker ML, Penarete-Vargas DM, Hamilton PT, Guérin A, Dubey JP, Perlman SJ, Spano F, Lebrun M, Boulanger MJ. Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):398-403.
• Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). [Academic Journal]Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: In Process; MEDLINE DOI: 10.1080/15548627.2015.1100356
• Wang K, Peng ED, Huang AS, Xia D, Vermont SJ, Lentini G, Lebrun M, Wastling JM, Bradley PJ. (2106) Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography. PLoS One. Mar 7;11(3):e0150561.
• Rommereim LM, Bellini V, Fox BA, Pètre G, Rak C, Touquet B, Aldebert D, Dubremetz JF, Cesbron-Delauw MF, Mercier C, Bzik DJ. (2016) Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii. PLoS One. Jul 26;11(7):e0159306.
• Jimenez-Ruiz E, Morlon-Guyot J, Daher W, Meissner M. (2016) Vacuolar protein sorting mechanisms in apicomplexan parasites. Mol Biochem Parasitol. Sep - Oct;209(1-2):18-25.
• Delgadillo RF, Parker ML, Lebrun M, Boulanger MJ, Douguet D. (2016) Stability of the Plasmodium falciparum AMA1-RON2 Complex Is Governed by the Domain II (DII) Loop. PLoS One. 2016 Jan 5;11(1):e0144764.

Team V. Molle

• S. Brelle, G. Baronian, S. Huc-Brandt, L.G. Zaki, M. Cohen-Gonsaud, M. Bischoff and V. Molle (2016) Phosphorylation-mediated regulation of the Staphylococcus aureus secreted tyrosine phosphatase PtpA. Biochemical and Biophysical Research Communications 469:619-625.
• M. Catel-Ferreira, S. Marti, L. Guillon, L. Jara, G. Coadou, V. Molle, E. Bouffartigues, G. Bou, I. Shalk, T. Jouenne, X. Vila-Farrés and Dé E (2016). The outer membrane porin OmpW of Acinetobacter baumannii is involved in iron uptake and colistin binding. FEBS Letters 590:224-231.
• M. Bischoff, S. Brelle, S. Minatelli and V. Molle (2016) Stk1-mediated phosphorylation stimulates the DNA-binding properties of the Staphylococcus aureus SpoVG transcriptional factor. Biochemical and Biophysical Research Communications 473:1223-1228.
• A. Gueho, C. Bosmani, N. Gopaldass, V. Molle, T. Soldati and F. Letourneur (2016) Dictyostelium EHD associates with Dynamin and participates in phagosome maturation. Journal of Cell Science 129:2354-2367.
• N-H Le, V. Molle, N. Eynard, M. Miras, A. Stella, F. Bardou, S. Galandrin, V. Guillet, G. André-Leroux, M. Bellinzoni, P.Alzari, L. Mourey, O. Burlet-Schiltz, M. Daffé and H. Marrakchi (2016) Ser/Thr phosphorylation regulates the Fatty Acyl-AMP Ligase activity of FadD32, an essential enzyme in mycolic acid biosynthesis. Journal of Biological Chemistry 291:22793-22805.
• A. K. Sharma, D. Arora, L. K. Singh, A. Gangwal, A. Sajid, V. Molle, Y. Singh, and V. K. Nandicoori (2016) Serine/threonine protein phosphatase PstP of Mycobacterium tuberculosis is necessary for accurate cell division and survival of pathogen. Journal of Biological Chemistry 291:24215-24230.
• Le Moigne C, Belon C, Goulard C, Accard G, Bernut A, Pitard B, Gaillard JL, Kremer L, Herrmann JL and Blanc-Potard AB. (2016) MgtC as a host-induced factor and vaccine candidate against Mycobacterium abscessus infection. Infect. Immun. ;84(10):2895-903.
• Belon C and Blanc-Potard AB. (2016) Intramacrophage survival for extracellular bacterial pathogens: MgtC as a key adaptive factor. Front Cell Infect Microbiol. doi: 10.3389/fcimb.2016.00052
• Belon C, Rosas Olvera M, Vives E, Kremer L, Gannoun-Zaki L, Blanc-Potard AB. (2016) Use of the Salmonella MgtR peptide as an antagonist of the Mycobacterium MgtC virulence factor. Future Microbiol. 11:215-25

Team M. Vidal

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). [Academic Journal] Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: In Process; MEDLINE DOI: 10.1080/15548627.2015.1100356

Team O. Radulescu / A. Parmeggiani

• Gorgoni B; Ciandrini L; McFarland MR; Romano MC; Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translation. [Academic Journal] Stansfield I Publisher: Oxford University Press NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res.
• Innocentini GCP, Forger M, Radulescu O, Antoneli F. Protein synthesis driven by dynamical stochastic transcription. Bulletin of mathematical biology (2016) 78: 110-131.DOI: 10.1007/s11538-015-0131-3
• Vakulenko S, Morozov I, Radulescu O. Maximal switchability of centralized networks. Nonlinearity (2016) 29:2327.
• Sommer-Simpson J, Reinitz J, Fridlyand L, Philipson L, Radulescu O. Hybrid Reductions of Computational Models of Ion Channels Coupled to Cellular Biochemistry. Lecture Notes in Computer Science (2016) 9859:273-288.
• Samal SS, Naldi A, Grigoriev D, Weber A, Théret Nathalie, Radulescu O. Geometric analysis of pathways dynamics: application to versatility of TGF-b receptors. Biosystems (2016) 149: 3-14.
• Innocentini G, Guiziou S, Bonnet J, Radulescu O. Analytic framework for a stochastic binary biological switch. Physical Review E (2016) 94: 062413.
• Gorgoni, Barbara, Ciandrini, Luca, McFarland, Matthew R, Romano, M Carmen, Stansfield, Ian. Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translation. Nucleic acids research (2016) 44: 9231—9244.
• Loukil, A., Izard, F., Georgieva, M., Mashayekhan, S., Blanchard, J.-M., Parmeggiani, A. and Peter, M. "Foci of cyclin A2 interact with actin and RhoA in mitosis", Scientific Reports 6, 2016, pp. 27215

Team G. Lutfalla

• Bernut A, Nguyen-Chi M, Halloum I, Herrmann JL, Lutfalla G, Kremer L (2016) Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking. PLOS Pathog 12: e1005986. doi:10.1371/journal.ppat.1005986
• Faure E, Campana M, Cunderlik R, Drblikova O, Duloquin L, Keller R, Lombardot B, Melani C, Remesikova M, Rizzi B, Savy T, Recher G, Zanella C, Kollar J, Villoutreix P, Delile J, Affaticati P, Maury, B, Colin I, Desnoulez S, Nief JY, Calvat P, Lutfalla G, Suret P, Doursat R, Sarti A, Mikula K, Peyriéras N, Bourgine P (2016) A workflow to process 3D+time images of developing organisms and reconstruct their cell lineage. Nat Commun 7:8674. doi:10.1038/ncomms9674
• Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, LeMoigne V, Vilchèze C, Lutfalla G, Herrmann JL, Jacobs WR Jr, Kremer L (2016) Deletion of a new dehydratase obliterates cording and virulence of rough Mycobacterium abscessus. Proc Natl Acad Sci USA 113:E4228-4237. doi:10.1073/pnas.1605477113
• Lin H, Andersen GR, Yatime L (2016) Crystal structure of human S100A8 in complex with zinc and calcium. BMC Struct Biol 16:8. doi:10.1186/s12900-016-0058-4
• Nguyen-Chi M, Laplace-Builhe B, Jorgensen C, Djouad F (2016) Deciphering the complexity of macrophage biology and function with the zebrafish model. Macrophage 3:e1260. doi:10.14800/Macrophage.1260
• Piazzon C, Lutfalla G, Forlenza M (2016) IL10, a tale of an evolutionary conserved cytokine across vertebrates. Crit Rev Immunol 36:99-129. doi:10.1615/CritRevImmunol.2016017480 
• Yatime L, Betzer C, Jensen RK, Mortensen S, Jensen PH, Andersen GR (2016) The structure of the RAGE:S100A6 complex reveals a new mode of homodimerization for S100 proteins. Structure 24, 2043-2052. doi:10.1016/j.str.2016.09.011
• Yatime L, Bajic G, Schatz-Jakobsen JA, Andersen GR (2016) Complement regulators and inhibitors in health and disease: a structural perspective. In K.A. Howard, T. Vorup-Jensen and D. Peer (eds.), Nanomedicine (pp. 13-42). CRS Book Series Advances in Delivery Science and Technology, Springer-Verlag New York. doi:10.1007/978-1-4939-3634-2_2

Team G. Uzé

• El Costa H, Gouilly J, Mansuy JM, Chen Q, Levy C, Cartron G, Veas F, Al-Daccak R, Izopet J, Jabrane-Ferrat N. (2016) ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy. Sci Rep. 6:35296.
• Tout M, Passot C, Cartron G, Paintaud G, Ternant D. (2016) Gota et al. on their article "the pharmacokinetics of Reditux™, a biosimilar of rituximab". Cancer Chemother Pharmacol. 78(6):1317-1318.
• Trusson R, Serre JE, Szwarc I, Brunot V, Garrigue V, Delmas S, Kanouni T, Cartron G, Mourad G. (2016) Treatment Response and Outcomes in Post-transplantation Lymphoproliferative Disease vs Lymphoma in Immunocompetent Patients. Transplant Proc. 48(6):1927-33.
• Reboursiere E, Le Bras F, Herbaux C, Gyan E, Clavert A, Morschhauser F, Malak S, Sibon D, Broussais F, Braun T, Fornecker LM, Garidi R, Tricot S, Houot R, Joly B, Abarah W, Choufi B, Pham AD, Gac AC, Fruchart C, Marin E, Safar V, Parcelier A, Maisonneuve H, Bachy E, Cartron G, Jaccard A, Tournilhac O, Rossi C, Schirmer L, Martignoles JA, Gaulard P, Tilly H, Damaj G; From the Lymphoma Study Association (LYSA) centers. (2016) Bendamustine for the treatment of relapsed or refractory peripheral T cell lymphomas: A French retrospective multicenter study. Oncotarget. 7(51):85573-85583.
• Azzaoui I, Uhel F, Rossille D, Pangault C, Dulong J, Le Priol J, Lamy T, Houot R, Le Gouill S, Cartron G, Godmer P, Bouabdallah K, Milpied N, Damaj G, Tarte K, Fest T, Roussel M. (2016) T-cell defect in diffuse large B-cell lymphomas involves expansion of myeloid-derived suppressor cells. Blood. 128(8):1081-92.
• Laurent C, Fabiani B, Do C, Tchernonog E, Cartron G, Gravelle P, Amara N, Malot S, Palisoc MM, Copie-Bergman C, Glehen AT, Copin MC, Brousset P, Pittaluga S, Jaffe ES, Coppo P. (2016) Immune-checkpoint expression in Epstein-Barr virus positive and negative plasmablastic lymphoma: a clinical and pathological study in 82 patients. Haematologica. 101(8):976-84.
• Krzywinska E, Cornillon A, Allende-Vega N, Vo DN, Rene C, Lu ZY, Pasero C, Olive D, Fegueux N, Ceballos P, Hicheri Y, Sobecki M, Rossi JF, Cartron G, Villalba M. (2016) CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential Activity. PLoS One. 21;11(4):e0150434.
• Ribrag V, Koscielny S, Bosq J, Leguay T, Casasnovas O, Fornecker LM, Recher C, Ghesquieres H, Morschhauser F, Girault S, Le Gouill S, Ojeda-Uribe M, Mariette C, Cornillon J, Cartron G, Verge V, Chassagne-Clément C, Dombret H, Coiffier B, Lamy T, Tilly H, Salles G. (2016) Rituximab and dose-dense chemotherapy for adults with Burkitt's lymphoma: a randomised, controlled, open-label, phase 3 trial. Lancet. 2016 387(10036):2402-11.
• Jourdan M, Cren M, Schafer P, Robert N, Duperray C, Vincent L, Ceballos P, Cartron G, Rossi JF, Moreaux J, Chopra R, Klein B. (2016) Differential effects of lenalidomide during plasma cell differentiation. Oncotarget. 7(19):28096-111.
• Gagez AL, Tuaillon E, Cezar R, Dartigeas C, Mahé B, Letestu R, Maisonneuve H, Gouilleux-Gruart V, Bollore K, Ferrant E, Aurran T, Feugier P, Leprêtre S, Cartron G. (2016) Response to rituximab in B-CLL patients is adversely impacted by frequency of IL-10 competent B cells and FcγRIIIa polymorphism. A study of FCGCLL/WM and GOELAMS groups. (2016) Blood Cancer J. 6:e389.
• Cartron G, Houot R, Kohrt HE. (2016) Scientific Significance of Clinically Insignificant FcγRIIIa-V158F Polymorphism. Clin Cancer Res. 22(4):787-9.
• Cartron G, Hourcade-Potelleret F, Morschhauser F, Salles G, Wenger M, Truppel-Hartmann A, Carlile DJ. (2016) Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma. Haematologica. 101(2):226-34.
• Walter HS, Rule SA, Dyer MJ, Karlin L, Jones C, Cazin B, Quittet P, Shah N, Hutchinson CV, Honda H, Duffy K, Birkett J, Jamieson V, Courtenay-Luck N, Yoshizawa T, Sharpe J, Ohno T, Abe S, Nishimura A, Cartron G, Morschhauser F, Fegan C, Salles G. (2016) A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies. Blood. 127(4):411-9.

Team M. Lebrun / C. Braun-Breton

• De Macêdo JP., Schumann Burkard G., Niemann M., Barrett MP., Vial H., Mäser P., Roditi I., Schneider A., Bütikofer P.(2015) An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei. PLoS Pathog. May 6;11(5):e1004875. doi: 10.1371/journal.ppat.1004875. eCollection.
  
• Contet A., Pihan E., Lavigne M., Wengelnik K., Maheshwari S., Vial H., Douguet D. & Cerdan R. (2015) Plasmodium falciparum CTP:phosphocholine cytidylyltransferase possesses two functional catalytic domains and is inhibited by a CDP-choline analog selected from a virtual screening., FEBS Letter, Apr 13; 589(9):992-1000. doi: 10.1016/j.febslet.2015.03.003. Epub 2015 Mar 13. PMID: 25771858
  
• Winkler M., Maynadier M., Wein S., Lespinasse MA., Boumis G., Miele AE., Vial H., Wong YS. (2015). Uncovering new structural insights for antimalarial activity from cost-effective aculeatin-like derivatives. Org Biomol Chem. 2015, 13(7):2064-77. doi: 10.1039/c4ob02459a. PMID: 25519040.
  
• Mbengue A., Vialla E., Berry L., Fall G., Audiger N., Demettre-Verceil E, Boteller D., Braun-Breton C.  (2015) New export pathway in Plasmodium falciparum-infected erythrocytes: role of the parasite group II chaperonin, PfTRiC. Traffic - 16(5):461-475
  
• Besteiro S., Blanc-Potard A., Bonazzi M., Briant L., Chazal N., Cornillot E., Lentini G., Matkovic R., Sanosyan A., Tuaillon E., Van de Perre P.  (2014) Montpellier Infectious Diseases - Pôle Rabelais (MID) 3rd annual meeting. Infect Genet Evol. 2015 Jun;32:161-4.
  
• Besteiro S. (2015) Toxoplasma control of host apoptosis: the art of not biting too hard the hand that feeds you. Microb Cell. 2(6): 178-181
  
• Pihan E., Delgadillo RF., Tonkin ML., Pugnière M., Lebrun M., Boulanger MJ., Douguet D. (2015) Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex. J Comput Aided Mol Des.
  
• Debaisieux S., Lachambre S., Gross A., Mettling C., Besteiro S., Yezid H., Henaff D., Chopard C., Mesnard JM., Beaumelle B. (2015) HIV-1 Tat inhibits phagocytosis by preventing the recruitment of Cdc42 to the phagocytic cup. Nat Commun.  4;6:6211
  
• Rugarabamu G., Marq JB., Guérin A., Lebrun M., Soldati-Favre D. (2015) Distinct contribution of Toxoplasma gondii rhomboid proteases 4 and 5 to micronemal protein protease 1 activity during invasion. Mol Microbiol. Apr 2.
  
• Lentini G., Kong-Hap M., El Hajj H., Francia M., Claudet C., Striepen B., Dubremetz JF., Lebrun M.  (2015) Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite. Cell Microbiol. 17(1):62-78.
  
• Morlon-Guyot J., Pastore S., Berry L., Lebrun M., Daher W.  (2015) Toxoplasma gondii Vps11, a subunit of HOPS and CORVET tethering complexes, is essential for the biogenesis of secretory organelles. Cellular Microbiology, 1157-1178.
  
• Daher W., Morlon-Guyot J., Sheiner L., Lentini G., Berry L., Tawk L., Dubremetz JF., Wengelnik K., Striepen B., Lebrun M. (2015) Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii. Cellular Microbiology, 559-578.
  
• Lévêque M., Berry L., Cipriano M., Nguyen Hoa-Mai., Striepen B., Besteiro S. (2015) Autophagy-related protein ATG8 has a non-canonical function for apicoplast inheritance in Toxoplasma gondii. Mbio. 2015 Oct 27;6(6). pii: e01446-15. doi: 10.1128/mBio.01446-15
  
• Risco-Castillo V., Topçu Selma., Marinach C., Manzon G., Bigorgne A.E., Briquet S., Baudin X., Lebrun M., Dubremetz J.F., and Olivier Silvie.  (2015) Malaria Sporozoites Traverse Host Cells within Transient Vacuoles.  Cell Host & Microbes. In press

 

Team V. Molle

• Bernut A., Belon C., Soscia C., Bleves S., Blanc-Potard AB. Intracellular phase for an extracellular bacterial pathogen: MgtC shows the way. Microbial Cell. In press
  
• Guzzo M., Agrebi R., Espinosa L., Baronian G.,  Molle V., Mauriello E.M., Brochier-Armanet C. and Mignot T. (2015) Evolution and Design Governing Signal Precision and Amplification in a Bacterial Chemosensory Pathway. PLoS Genetics 20;11(8):e1005460. doi: 10.1371/journal.pgen.1005460.
  
• Belon C., Soscia C., Bernut A., Laubier A., Bleves S., Blanc-Potard AB. (2015) A Macrophage Subversion Factor Is Shared by Intracellular and Extracellular Pathogens. PLoS Pathog. 11(6):e1004969. doi: 10.1371/journal.ppat.1004969. eCollection
  
• Baronian G., Ginda K., Berry L., Cohen-Gonsaud M., Zakrzewska-Czerwińska J., Jakimowicz D. And Molle V. (2015) Phosphorylation of Mycobacterium tuberculosis ParB participates in regulating the ParABS chromosome segregation system. PLoS One 10:e0119907.
• Monteil A, Chausson P, Boutourlinsky K, Mezghrani A, Huc-Brandt S, Blesneac I, Bidaud I, Lemmers C, Leresche N, Lambert RC, Lory P. Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop. J Biol Chem. 2015 Jun 26;290(26):16168-76. 
  
  

Team M. Vidal

• Blanc L., Papoin J., Debnath G., Vidal M., Amson R., Telerman A., An X., and Mohandas N. (2015) Defective erythropoiesis leads to microcytic anemia in the TSAP6/Steap3 null mouse model. Am. J. Hematol.  Mar;90 (3) : 235-41.doi: 10.1002/ajh.23920
  
• Le Goff  E., Martinand-Mari C., Martin M., Feuillard J., Boublik Y., Godefroy N., Mangeat P., Baghdiguian S. and Cavalli G. (2015)  Enhancer of zeste acts as a major developmental regulator of Ciona intestinalis embryogenesis. Biology Open August 14, doi:10.1242/bio.010835 
  
  

Team O. Radulescu / A. Parmeggiani

• Sanchez A., Cattoni D., Walter J.-C., Rech J., Parmeggiani A., Nollmann M., Bouet J.-Y. (2015) Stochastic Self-Assembly of ParB Proteins Builds the Bacterial DNA Segregation Apparatus, Cell Systems, vol. 1 p.163-173
  
• Golushko I.Y., Rochal S.B., Parmeggiani A., Lorman V.L. (2015) Instabilities and shape variation phase transitions in tubular lipid membranes, arXiv preprint arXiv :1501.00258 
  
• Baiesi M., Carlon E., Parmeggiani A. (2015) Fundamental Problems in Statistical Physics XIII Special Issue, Physica A Statistical Mechanics and its Applications 418, 1-5
  
• Ciandrini L. (2015) Molecular motors with a stepping cycle: from theory to experiments.  Proceedings of Traffic and Granular Flow '13, pp 619-627, Springer 
  
• Samal S.S., Grigoriev D., Fröhlich H., Radulescu O. (2015): Analysis of reaction network systems using tropical geometry. In: V.P. Gerdt, W. Koepf, W.M. Seiler, E.V. Vorozhtsov (eds.) Computer Algebra in Scientific Computing, 17th International Workshop (CASC 2015), Lecture Notes in Computer Science, vol. 9301, pp. 422--437. Springer, Aachen, Germany
• Samal SS, Grigoriev D, Froehlich H, Weber A, Radulescu O. A Geometric Method for Model Reduction of Biochemical Networks with Polynomial Rate Functions. Bulletin of Mathematical Biology (2015) 77: 2180-2211.
  
• Radulescu O., Vakulenko S., Grigoriev D. (2015) : Model reduction of biochemical reactions networks by tropical analysis methods. Mathematical Models of Natural Phenomena 10(3), 124-138
  
• Fardin M-A., Radulescu O., Morozov A., Cardoso O., and Lerouge S..  (2015) Stress diffusion in shear banding wormlike micelles. Journal of Rheology, in press
  
• Radulescu O., Samal S.S., Naldi A., Grigoriev D. and Weber A. (2015) Symbolic dynamics of biochemical pathways as finite state machines. 13th International Conference (CMSB 2015), Lecture Notes in Computer Science, in press. 
  
  

Team G. Lutfalla

• Bernut A, Dupont CM, Sahuquet A, Herrmann JL, Lutfalla G, Kremer L (2015) Deciphering and imaging pathogenesis and cording of Mycobacterium abscessus in zebrafish embryos. J Vis Exp 103:e53130. doi:10.3791/53130
• Hirsinger E, Carvalho JE, Chevalier C, Lutfalla G, Nicolas JF, Peyriéras N, Schubert M (2015) Expression of fluorescent proteins in Branchiostoma lanceolatum by mRNA injection into unfertilized oocytes. J Vis Exp 95:52042. doi:10.3791/52042
• Laursen M, Gregersen JL, Yatime L, Nissen P, Fedosova NU (2015) Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared to the ouabain-bound complex. Proc Natl Acad Sci USA 112, 1755-1760. doi:10.1073/pnas.1422997112
• Madgwick A, Fort P, Hanson PS, Thibault P, Gaudreau MC, Lutfalla G, Möröy T, Abou Elela S, Chaudhry B, Elliott DJ, Morris CM, Venables JP (2015) Neural differentiation modulates the vertebrate brain specific splicing program. PLoS One 10:e0125998. doi:10.1371/journal.pone.0125998
• Nguyen-Chi M, Laplace-Builhe B, Travnickova J, Luz-Crawford P, Tejedor G, Phan QT, Duroux-Richard I, Levraud JP, Kissa K, Lutfalla G, Jorgensen C, Djouad F (2015) Identification of polarized macrophage subsets in zebrafish. eLife 4:e07288. doi:10.7554/eLife.07288
• Yatime L, Maasch C, Hoehlig K, Klussmann S, Andersen GR, Vater A (2015) Structural basis for the inhibition of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer. Nat Commun 6:6481. doi:10.1038/ncomms7481
• Debaisieux S., Lachambre S., Gross A., Mettling C., Besteiro S., Yezid H., Henaff D., Chopard C., Mesnard JM., Beaumelle B. (2015) HIV-1 Tat inhibits phagocytosis by preventing the recruitment of Cdc42 to the phagocytic cup. Nat Commun 6:6211. doi: 10.1038/ncomms7211

Team K. Kissa

• Travnickova J., Tran Chau V., Julien E., Mateos-Langerak J., Gonzalez C., Lelièvre E., Lutfalla G., Tavian M., Kissa K. (2015) Primitive macrophages control HSPC mobilization and definitive haematopoiesis. Nat Commun. Feb 17;6:6227. 
  
  

Team G. Uzé

• Zhang, X., Bogunovic, D., Payelle-Brogard, B., Francois-Newton, V., Speer, S., Yuan, C., Volpi., S., Li, Z., Sanal, O., Mansouri, D., Tezcan, I., Rice, G.I., Chen, C., Mansouri, N., Mahdaviani, S-A., Itan, Y., Boisson, B., Okada, S., Zeng, L., Wang, X., Jiang, H., Liu, W., Han, T., Liu, D., Ma., T., Wang, B., Liu, M., Liu, J., Wang, Q.K., Yalnizoglu, D., Radoshevich, L., Uzé, G., Gros, P., Rozenberg, F., Zhang, S-Y., Jouanguy, E., Bustamante, J., García-Sastre, A., Abel, L., Lebon, P., Notarangelo, L.D., Boisson-Dupuis, S., Crow, Y.J., Casanova, J-L. and Pellegrini, S.(2015) Human intracellular ISG15 prevents IFN-α/β over-amplification and auto-inflammation. Nature. 517. 89-93.
  
• Sultanik P-S., Casrouge  A., Alanio C., Mottez E., Rosa-Hézode I., Hézode C., Renard P., Bousquet L., Pelle  P., Uzé G., Pol S., Albert M.L. and Mallet V. J. (2015) Baseline sensitivity of T cells to alpha-interferon correlates with sustained virological response to IFN-based triple therapy in HCV infection. Viral Hepatitis.  22(6):524-34. doi: 10.1111/jvh.12355. Epub 2014 Nov 10.
  
• Uzé G. and Tavernier, J. (2015) High efficiency targeting of IFN-α activity: possible applications in fighting tumors and infections. Cytokine and Growth Factor Reviews. 26(2):179-82. doi: 10.1016/j.cytogfr.2014.10.006
  
• Wilmes S., Beutel O., Li Z., Franҫois-Newton V., Richter C.P., Janning D., Kroll C., Hanhart P., Hötte K., You C., Uzé G., Pellegrini S.and Piehler J. (2015) Receptor dimerization dynamics as regulatory valve for plasticity of type I interferon signalling. J. Cell Biol. 209: 579-593.
  
• Paul F., Pellegrini S. and Uzé G. IFNA2: The prototypic human alpha interferon. (2015) Gene. 567: 132-137.
  
• Livingstone M., Sikström K., Robert P.A., Uzé G., Larson O. and Pellegrini S. Assessment of mTOR-dependent translational regulation of interferon stimulated genes. (2015) PLos One. 10(7): e0133482.
  
  

Team M. Lebrun / C. Braun-Breton

• Penarete-Vargas DM., Boisson A., Urbach S., Chantelauze H., Peyrottes S., Fraisse L., Vial HJ. (2014) A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using Photocrosslinking and Click Chemistry. PLoS One, 9(12):e113918. doi: 10.1371.
• Nagy GN., Marton L., Contet A., Ozohanics O., Ardelean LM., Révész A., K Vékey K., Irimie FD.,  Vial H., Cerdan R., Vertessy BG. (2014) Composite aromatic box: a structural motif for binding and enzyme-catalyzed conversion of quaternary ammonium substrates, Angew Chem Int Ed Engl. 53(49):13471-6. doi: 10.1002/anie.201408246; PMID: 25283789
  
• Vial H., and Wengelnik K. (2014) Phospholipid metabolism, Encyclopedia of Malaria, (M Hommel and PG Kremsner Edit),  Springer Press
  
• Wein S., Tran Van Ba C., Maynadier M., Y. Bordat., Perez J., Peyrottes S., Fraisse L. & Vial HJ. (2014) New insight in the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium - a new type of antimalarial. Antimicrobial Agents and Chemotherapy, 58(9), 5519-5527.
  
• Ruiz J., Azémaa J., Payrastre C., Baltas M., Tuccio B., Vial H., André-Barrès C. (2014)  Antimalarial bicyclic peroxides belonging to the G-factor family: mechanistic aspects of their formation and iron (II) induced reduction, Current Topics in Medicinal Chemistry, 14(14):1668-1683; PMID: 25116578, ISSN: 1568-0266
  
• Peyrotte S., Caldarelli S., Wein S., Périgaud C., and Vial H. (2014) Exploring prodrug approaches for Albitiazolium and its analogues, Current Topics in Medicinal Chemistry ;14(14):1653-1667; PMID: 25116583, ISSN: 1568-0266
  
• Ruiz J., Mallet-Ladeira S., Maynadier M., Vial H. and André-Barrès C. (2014) Design, synthesis and evaluation of new tricyclic endoperoxides as potential antiplasmodial agents. Org Biomol Chem. 12(28):5212-21
  
• Saidani N., Botte C., Deligny M., Bonneau AL., Reader J., LasselinR., Merer G., Niepceron A.,  Brossier F., Cintrat J.C., Rousseau B., Birkholtz LM., Cesbron-Delauw MF., Dubremetz JF., Mercier C., Vial H., Lopez R., and Marechal E. (2014) Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolidinone analogs, Antimicrob. Agents Chemother 58(5):2586. DOI: 10.1128/AAC.01445-13, PMID: 24550329
  
• Degardin M., Wein S., Duckert JF., Maynadier M., Guy A., Durand T., R Escale R., Vial H. and Vo-Hoang Y.  (2014)Development of the first oral bioprecursors of bis-alkylguanidine antimalarial drugs., ChemMedChem.  9:300-4. doi: 10.1002/cmdc.201300419; PMID: 24403182.
  
• Lamarque MH., Roques M., Kong-Hap M., Tonkin ML., Rugarabamu G., Marq JB., Penarete-Vargas DM., Boulanger MJ., Soldati-Favre D., Lebrun M.  (2014) Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites. Nat Commun.  Jun 17;5:4098. 
  
• Morlon-Guyot J., Berry L., Chen CT., Gubbels MJ., Lebrun M., Daher W. (2014) The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival. Cell Microbiol. 95-114.
  
• Swaffer, B. A., Vial, H. M., King, B. J., Daly, R., Frizenschaf, J., and Monis, P. T. (2014) Investigating source water Cryptosporidium concentration, species and infectivity rates during rainfall-runoff in a multi-use catchment. Water Res 67, 310-320
• Salamun J., Kallio J., Daher W., Soldati-Favre D., and Kursula I. (2014) Structure of Toxoplasma gondii coronin: an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress. FASEB Journal, 4729-4747.
• Niehus S., Smith TK., Azzouz N., Campos MA., Dubremetz JF., Gazzinelli RT., Schwarz RT., Debierre-Grockiego F.  (2014) Virulent and avirulent strains of Toxoplasma gondii which differ in their glycosylphosphatidylinositol content induce similar biological functions in macrophages. PLoS One.  Jan 28;9(1):e85386.
• Fond G., Macgregor A., Tamouza R., Hamdani N., Meary A., Leboyer M., Dubremetz JF.  (2014) Comparative analysis of anti-toxoplasmic activity of antipsychotic drugs and valproate. Eur Arch Psychiatry Clin Neurosci.  Mar;264(2):179-83.

Team V. Molle

• Baïlo N., Cosson P., Charette S.J., Paquet V.E., Doublet P., Letourneur F. (2014) Defective lysosome maturation and Legionella pneumophila replication in Dictyostelium cells mutant for the Arf GAP ACAP-A. J Cell Sci. Nov 1;127(21):4702-13. doi: 10.1242/jcs.154559. Epub 2014 Sep 4. PMID: 25189617.
• Belon C., Gannoun-Zaki L., Lutfalla G., Kremer L., Blanc-Potard A. (2014) Mycobacterium marinum MgtC plays a role in phagocytosis but is dispensable for intracellular multiplication. PLoSOne. 29;9(12):e116052. doi:10.1371/journal.pone.0116052. eCollection.
  
• Gannoun-Zaki L., Belon C., Dupont C., Hilbert F., Kremer L., Blanc-Potard A. (2014).Overexpression of the Salmonella KdpF membrane peptide modulates expression of kdp genes and intramacrophage growth. FEMS Microbiol Lett. 359(1):34-41. doi: 10.1111/1574-6968.12559. Epub 2014 Sep 8.
  
• Alibaud L., Pawelczyk J., Gannoun-Zaki L., Singh VK., Rombouts Y., Drancourt M., Dziadek J., Guérardel Y., Kremer L. (2014) Increased phagocytosis of Mycobacterium marinum mutants defective in lipooligosaccharide production: a structure-activity relationship study. J Biol Chem. 3;289(1):215-28. doi: 10.1074/jbc.M113.525550. Epub 2013 Nov 14.
  
• Canova M.J., and Molle V. (2014) Bacterial Serine/Threonine Protein Kinases in Host-Pathogen Interactions. J Biol Chem. 289:9473-79.
  Leiba J., Carrère-Kremer S., Blondiaux N., Dimala M.M., Wohlkönig A., Baulard A., Kremer L., and  Molle V. (2014) The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation. Biochem Biophys Research Commun 446:1132-1138.
  
• Leiba J, Carrère-Kremer S, Blondiaux N, Dimala MM, Wohlkönig A, Baulard A, Kremer L, Molle V. The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation. Biochem Biophys Res Commun. 2014 Apr 18;446(4):1132-8.
• Canova M.J., Baronian G., Brelle S., Cohen-Gonsaud M., Bischoff M., and Molle V. (2014) A novel mode of regulation of the Staphylococcus aureus Vancomycin-resistance-associated response regulator VraR mediated by Stk1 protein phosphorylation. Biochem Biophys Research Commun 447:165-171.
  
• Vilchèze C., Molle V., Carrère-Kremer S., Leiba J., Mourey L., Shenai S., Baronian G., Tufariello J.,   Hartman T., Veyron-Churlet R., Trivelli X., Tiwari S., Weinrick B., Alland D., Guérardel Y., Jacobs W.R., Jr., and Kremer L. (2014) Phosphorylation of KasB Regulates Virulence and Acid-Fastness in Mycobacterium tuberculosis. Plos Pathogens 8:10(5):e1004115.
  
• Hartmann T., Baronian G., Nippe N., Voss M., Schulthess B., Wolz C., Eisenbeis J., Schmidt-Hohagen K., Gaupp R., Sunderkötter C., Beisswenger C., Bals R., Somerville G.A., Herrmann M., Molle V., and Bischoff M. (2014) The catabolite control protein E (CcpE) affects virulence determinant production and pathogenesis of Staphylococcus aureus. J Biol Chem 289:29701-29711.
  
• Mouammine, Lanois A., Pagès S., Lafay B., Molle V., Canova M., Girard P.A., Duvic B., Givaudan A. and Gaudriault S. (2014) Ail and PagC-related proteins in the entomopathogenic bacteria of Photorhabdus genus. PLoS One 9:e110060.
  
• Arora G., Sajid A., Singhal A., Joshi J., Virmani R., Gupta M., Verma N., Maji A., Misra R., Baronian G., Pandey A.K., Molle V. and Singh Y. (2014) Identification of Ser/Thr kinase and forkhead associated domains in Mycobacterium ulcerans: characterization of novel association between protein kinase Q and MupFHA. PLoS Neglected Tropical Diseases 8:e3315.
  
• Holečková N., Doubravová L., Massidda O., Molle V., Buriánková K., Benada O., Kofroňová O., Ulrych A. and Branny P. (2014) LocZ is a new cell division protein involved in proper septum placement in Streptococcus pneumoniae. MBio. 6(1):e01700-14.

Team O. Radulescu / A. Parmeggiani

• Ciandrini L., Neri I., Walter J.C., Dauloudet O., Parmeggiani A., Motor protein traffic regulation by supply-demand balance of resources. Physical Biology 11 (2014), 056006-1/17, selected as the Physical Biology Highlights of 2014, http ://iopscience.iop.org/1478-3975/page/Highlights-of-2014
  
• Rohani N., Parmeggiani A., Winklbauer R., Fagotto F. Variable Combinations of Specific Ephrin Ligand/Eph Receptor Pairs Control Embryonic Tissue Separation PLoS Biology 12 (2014), e1001955-1/21, Synopsis by R. Robinson,“Bind and Separate : How Ephrins and Their Receptors Create Tissue Boundaries”, PLoS, Biol 12 (2014), e1001956.
  
• Ciandrini L., Romano M.C., Parmeggiani A., Stepping and crowding of molecular motors : statistical kinetics from an exclusion process perspective - Biophysical Journal 107 (2014), 1176-1184
  
• Parmeggiani A., Neri I., Kern N. (2014) Modelling Collective Cytoskeletal Transport and Intracellular Traffic - The Impact of Applications on Mathematics - 1-25
  
• Noel V., Grigoriev D., Vakulenko S., Radulescu O. (2014) Tropical and Idempotent Mathematics and Applications, Contemporary Mathematics vol. 616, chap. Tropicalization and tropical equilibration of chemical reactions. American Mathematical Society.
• Soliman S., Fages F., Radulescu O. (2014) : A constraint solving approach to model reduction by tropical equilibration. Algorithms for Molecular Biology 9(1), 24.

Team G. Lutfalla

• Nguyen-Chi M, Phan QT, Gonzalez C, Dubremetz JF, Levraud JP, et al. (2014) Transient infection of the zebrafish notochord with E. coli induces chronic inflammation. Dis Model Mech 7:871-882. doi:10.1242/dmm.014498
• Bernut A, Herrmann JL, Kissa K, Dubremetz JF, Gaillard JF, Lutfalla G, Kremer L (2014) Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation. Proc Natl Acad Sci USA 111:E943-952. doi:10.1073/pnas.1321390111
• Fontenille L, Rouquier S, Lutfalla G, Giorgi D (2014) Microtubule-associated protein 9 (Map9/Asap) is required for the early steps of zebrafish development. Cell Cycle 13:1101-1114. doi:10.4161/cc.27944
• Siupka P, Hamming OJ, Frétaud M, Luftalla G, Levraud JP, Hartmann R (2014) The crystal structure of zebrafish IL-22 reveals an evolutionary conserved structure highly similar to that of human IL-22 and IFNλ. Genes Immun 15:293-302. doi:10.1038/gene.2014.18
• Bernut A, Le Moigne V, Lesne T, Lutfalla G, Herrmann JL, Kremer L (2014) In vivo assessment of drug efficacy against Mycobacterium abscessus using the embryonic zebrafish test system. Antimicrob Agents Chemother 58:4054-4063. doi:10.1128/AAC.00142-14
• Belon C, Gannoun-Zaki L, Lutfalla G, Kremer L, Blanc-Potard AB (2014) Mycobacterium marinum MgtC plays a role in phagocytosis but is dispensable for intracellular multiplication. PLoS One 9:e116052.doi:10.1371/journal.pone.0116052
• Graciarena M., Dambly-Chaudière C., Ghysen A., (2014) Dynamics of axonal regeneration in adult and aging zebrafish reveal the promoting effect of a first lesion. Proc Natl Acad Sci USA 111(4):1610-5. doi:10.1073/pnas.1319405111
  
• Duquenne C, Psomas C, Gimenez S, Guigues A, Carles MJ, Barbuat C, Lavigne JP, Sotto A, Reynes J, Guglielmi P, Mettling C, François V, Corbeau P (2014) The Two Human CXCR4 Isoforms Display Different HIV Receptor Activities: Consequences for the Emergence of X4 Strains. J Immunol 193:4188-4194. doi:10.4049/jimmunol.1303298
• Hamzé M, Desmetz C, Guglielmi P (2014) B lymphocytes: a promising target to treat atherosclerosis? Med Sci 30:874-881. doi:10.1051/medsci/20143010014

Team K. Kissa

• Faucherre A., Kissa K., Nargeot J., Mangoni ME., Jopling C. (2014). Piezo1 plays a role in erythrocyte volume homeostasis. Haematologica. Jan; 99 (1):70-5.
• Choorapoikayil S, Kers R, Herbomel P, Kissa K, den Hertog J. (2014) Pivotal role of Pten in the balance between proliferation and differentiation of hematopoietic stem cells in zebrafish. Blood. 2014 Jan 9;123(2):184-90.

Team G. Uzé

• Garcin G., Paul F., Staufenbiel, M., Bordat Y., Van der Heyden, J., Wilmes, S., Cartron G.,4, Apparailly, F., De Koker, S., Piehler, J., Tavernier, J. and Uzé G. (2014) High efficiency cell−specific targeting of cytokine activity. Nature Commun. 5:3016 doi: 10.1038/ncomms4016.
• Sistigu  A., Yamazaki T., Vacchelli E., Chaba K., Enot D.P., Adam J., Vitale I., Goubar A., Baracco E.E., Remédios C., Fend L., Hannani D., Aymeric L., Ma Y., Niso-Santano M., Kepp O., Schultze J.L., Tüting T., Belardelli F., Bracci L., La Sorsa V., Ziccheddu G., Sestili P., Urbani F., Delorenzi M., Lacroix-Triki  M., Quidville V., Conforti R., Spano J-P., Pusztai L., Poirier-Colame V., Delaloge, S., Penault-Llorca F., Ladoire S., Arnould L., Cyrta J., Marie-Charlotte Dessoliers M-C., Eggermont A., Bianchi M.E., Pittet M., Engblom C., Pfirschke C., Préville X., Uzé G., Schreiber R.D., Chow M.T., Smyth M.J., Proietti  E., André F., Kroemer G. and Zitvogel L. (2014) Cancer cell-autonomous contribution of Type 1 interferon signaling to the efficacy of chemotherapy. Nature Medecine. 11. 1301-1309.
• Tomasello E., Pollet E., Vu-Manh T-P., Uzé G. and Dalod M. (2014) Harnessing mechanistic knowledge on beneficial versus deleterious IFN-I effects to design innovative immunotherapies targeting cytokine activity to specific cell types. Frontiers in Immunology. 5. 526.
• Comet N.R., Aguiló J.I., Rathoré M.G., Catalán E., Garaude J., Uzé G., Naval J., Pardo J., Villalba M., and Anel A. (2014) IFN-α signaling through PKC-θ is essential for anti-tumoral NK cell function Oncoimmunology. 3. e948705.
• Cartron G., de Guibert S., Dilhuydy MS., Morschhauser F., Leblond V., Dupuis J., Mahe B., Bouabdallah R., Lei G., Wenger M., Wassner-Fritsch E.; Hallek M. (2014) Obinutuzumab (GA101) in relapsed/refractory chronic lymphocytic leukemia: final data from the phase 1/2 GAUGUIN study.Blood. 124(14):2196-202. doi: 10.1182/blood-2014-07-586610. Epub 2014 Aug 20.
• Gagez AL., Cartron G. (2014) Obinutuzumab: a new class of anti-CD20 monoclonal antibody.Curr Opin Oncol. 26(5):484-91. doi: 10.1097/CCO.0000000000000107.
• Duroux-Richard I, Pers YM, Fabre S, Ammari M, Baeten D, Cartron G, Touitou I, Jorgensen C, Apparailly F (2014) Circulating miRNA-125b is a potential biomarker predicting response to rituximab in rheumatoid arthritis. Mediators Inflamm. 2014:342524.
• Ouedraogo DE, Bollore K, Viljoen J, Foulongne V, Reynes J, Cartron G, Vendrell JP, Van de Perre P, Tuaillon E (2014) Comparison of EBV DNA viral load in whole blood, plasma, B-cells and B-cell culture supernatant. J Med Virol. 86(5):851-6.