Plasmodium genome plasticity (JJ. Lopez-Rubio)

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We are an ATIP-AVENIR team studying Plasmodium falciparum nuclear biology.
Research projects

Theme 1: Genome Plasticity

Theme leader: Dr. Jose-Juan Lopez-Rubio 

Plasmodial gene regulation
Each of the stages of the parasite's life cycle requires a distinct gene expression profile. We investigate molecular mechanisms underlying gene expression in malaria parasites, such as chromatin and DNA secondary structures.

Telomere DNA biology
Telomeres are specialized protein-DNA structures that protect chromosome ends from degradation and fusion, and are essential for complete replication of chromosomes. We are interested in Plasmodium telomeres since they provide a functional and structural support for antigenic variation and evolution of subtelomeric virulence gene families.


Theme 2: DNA Replication

Theme leader: Dr. Ana Rita Gomes


 

Team members
Alumni

Head of the team


Jose-Juan Lopez-Rubio
Research Associate (CR) INSERM
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JOB OFFERS / INTERNSHIPS

LPHI  Laboratory of Pathogen Host Interactions
UMR 5235 - Université Montpellier
Place Eugène Bataillon, Bât. 24, CC107, 2ème étage
34095 Montpellier cedex 5

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