Publications- Team 7
2024
Weimann A, Dinan AM, Ruis C, Bernut A, Pont S, Brown K, Ryan J, Santos L, Ellison L, Ukor E, Pandurangan AP, Krokowski S, Blundell TL, Welch M, Blane B, Judge K, Bousfield R, Brown N, Bryant JM, Kukavica-Ibrulj I, Rampioni G, Leoni L, Harrison PT, Peacock SJ, Thomson NR, Gauthier J, Fothergill JL, Levesque RC, Parkhill J, Floto RA (2024) Evolution and host-specific adaptation of Pseudomonas aeruginosa. Science 385(6704):eadi0908. doi:10.1126/science.adi0908
Hajjar H, Berry L, Wu Y, Touqui L, Vergunst AC, Blanc-Potard AB (2024) Contribution of intramacrophage stages to Pseudomonas aeruginosa infection outcome in zebrafish embryos: insights from mgtC and oprF mutants. Sci Rep 14(1):6297. doi:10.1038/s41598-024-56725-8
Leiba J, Sipka T, Begon-Pescia C, Bernardello M, Tairi S, Bossi L, Gonzalez AA, Mialhe X, Gualda E, Loza-Alvarez P, Blanc-Potard A, Lutfalla G, Nguyen-Chi M (2024) Dynamics of macrophage polarization support Salmonella persistence in a whole living organism. Elife 13:e89828. doi:10.7554/eLife.89828
2023
Rahimova R, Nogaret P, Huteau V, Gelin M, Clément DA, Labesse G, Pochet S, Blanc-Potard AB, Lionne C (2023) Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase. FEBS J 290:482-501. doi:10.1111/febs.16604
2022
Le Moigne V, Rodriguez Rincon D, Glatigny S, Dupont CM, Langevin C, Ait Ali Said A, Renshaw SA, Floto RA, Herrmann JL, Bernut A (2022) Roscovitine worsens Mycobacterium abscessus infection by reducing DUOX2-mediated neutrophil response. Am J Respir Cell Mol Biol 66:439-451. doi:10.1165/rcmb.2021-0406OC
2021
Sacher-Pirklbauer A, Klein-Jöbstl D, Sofka D, Blanc-Potard AB, Hilbert F (2021) Phylogenetic Groups and Antimicrobial Resistance Genes in Escherichia coli from Different Meat Species. Antibiotics 10:1543. doi:10.3390/antibiotics10121543
Pont S, Blanc-Potard AB (2021) Zebrafish Embryo Infection Model to Investigate Pseudomonas aeruginosa Interaction With Innate Immunity and Validate New Therapeutics. Front Cell Infect Microbiol 11:745851. doi:10.3389/fcimb.2021.745851
Nogaret P, El Garah F, Blanc-Potard AB (2021) A Novel Infection Protocol in Zebrafish Embryo to Assess Pseudomonas aeruginosa Virulence and Validate Efficacy of a Quorum Sensing Inhibitor In Vivo. Pathogens 10:401. doi:10.3390/pathogens10040401
Moussouni M, Berry L, Sipka T, Nguyen-Chi M, Blanc-Potard AB (2021) Pseudomonas aeruginosa OprF plays a role in resistance to macrophage clearance during acute infection. Sci Rep 11, 359. doi: 0.1038/s41598-020-79678-0
2020
Bernut A, Loynes CA, R Floto A, Renshaw SA (2020) Deletion of cftr Leads to an Excessive Neutrophilic Response and Defective Tissue Repair in a Zebrafish Model of Sterile Inflammation. Front Immunol 11, 1733. doi:10.3389/fimmu.2020.01733
2016
Bernut A, Nguyen-Chi M, Halloum I, Herrmann JL, Lutfalla G, Kremer L (2016) Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking. PLoS Pathog 12: e1005986. doi:10.1371/journal.ppat.1005986
Halloum I, Carrère-Kremer S, Blaise M, Viljoen A, Bernut A, LeMoigne V, Vilchèze C, Lutfalla G, Herrmann JL, Jacobs WR Jr, Kremer L (2016) Deletion of a new dehydratase obliterates cording and virulence of rough Mycobacterium abscessus. Proc Natl Acad Sci USA 113:E4228-4237. doi:10.1073/pnas.1605477113