Publications – Theme 1 (R. Cerdan)
Recent publications
Mohamed BS, Nguyen MC, Wein S, Uttaro JP, Robert X, Violot S, Ballut L, Jugnarain V, Mathé C, Cerdan R, Aghajari N, Peyrottes S (2023) Purine containing carbonucleoside phosphonate analogues as novel chemotype for Plasmodium falciparum Inhibition. Eur J Med Chem 258:115581. doi:10.1016/j.ejmech.2023.115581
Lohia R, Allegrini B, Berry L, Guizouarn H, Cerdan R, Abkarian M, Douguet D, Honoré E, Wengelnik K (2023) Pharmacological activation of PIEZO1 in human red blood cells prevents Plasmodium falciparum invasion. Cell Mol Life Sci 80:124. doi:10.1007/s00018-023-04773-0
Gazanion E, Lacroix L, Alberti P, Gurung P, Wein S, Mergny JL, Gomes AR* and Lopez-Rubio JJ* (2020) Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. PLoS Genet 16:e1008917. doi:10.1371/journal.pgen.1008917. *Co-senior authorship
Cheviet T, Wein S, Bourchenin G, Lagacherie M, Périgaud C, Cerdan R*, Peyrottes S* (2020) β-Hydroxy- A nd β-Aminophosphonate Acyclonucleosides as Potent Inhibitors of Plasmodium falciparum Growth. J Med Chem 63:8069-8087. doi:10.1021/acs.jmedchem.0c00131.*Co-senior authorship
Berger O, Ortial S, Wein S, Denoyelle S, Bressolle F, Durand T, Escale R, Vial HJ, Vo-Hoang Y (2019) Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials. Bioorg Med Chem Lett 29:2203-2207. doi:10.1016/j.bmcl.2019.06.045
Wein S, Ghezal S, Buré C, Maynadier M, Périgaud C, Vial HJ, Lefebvre-Tournier I, Wengelnik K, Cerdan R (2018) Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite. J Lipid Res 59:1461-1471. doi:10.1194/jlr.M085589
Guca E, Nagy GN, Hajdú F, Marton L, Izrael R, Hoh F, Yang Y, Vial H, Vértessy BG, Guichou JF, Cerdan R (2018) Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep 8:11215. doi:10.1038/s41598-018-29500-9
Berry L, Chen CT, Francia ME, Guerin A, Graindorge A, Saliou JM, Grandmougin M, Wein S, Bechara C, Morlon-Guyot J, Bordat Y, Gubbels MJ, Lebrun M, Dubremetz JF, Daher W (2018) Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny. Cell Mol Life Sci 75:4417-4443. doi:10.1007/s00018-018-2889-6
Wein S, Taudon N, Maynadier M, Tran Van Ba C, Margout D, Bordat Y, Fraisse L, Wengelnik K, Cerdan R, Bressolle-Gomeni F, Vial HJ (2017) High Accumulation and In Vivo Recycling of the New Antimalarial Albitiazolium Lead to Rapid Parasite Death. Antimicrob Agents Chemother 61:e00352-17. doi:10.1128/AAC.00352-17
Francisco Hilario F, Traoré M, Zwick V, Berry L, Simões-Pires C, Cuendet M, Fantozzi N, Pereira de Freitas R, Maynadier M, Wein S, Vial H, Wong, YS (2017) Synthesis of an uncharged tetra-cyclopeptide acting as transmembrane carrier: enhanced cellular and nuclear uptake. Org Lett 19:612-615. doi:10.1021/acs.orglett.6b03776
Traoré MDM, Zwick V, Simões-Pires CA, Nurisso A, Issa M, Cuendet M, Maynadier M, Wein S, Vial H, Jamet H, Wong YS (2017) Hydroxyl Ketone-Based Histone Deacetylase Inhibitors To Gain Insight into Class I HDAC Selectivity versus That of HDAC6. ACS Omega 2:1550-1562. doi:10.1021/acsomega.6b00481
Contet A, Pihan E, Lavigne M, Wengelnik K, Maheshwari S, Vial H, Douguet D, Cerdan R (2015) Plasmodium falciparum CTP:phosphocholine cytidylyltransferase possesses two functional catalytic domains and is inhibited by a CDP-choline analog selected from a virtual screening. FEBS Letter 589:992-1000. doi:10.1016/j.febslet.2015.03.003
Winkler M, Maynadier M, Wein S, Lespinasse MA, Boumis G, Miele AE, Vial H, Wong YS (2015) Uncovering new structural insights for antimalarial activity from cost-effective aculeatin-like derivatives. Org Biomol Chem 13:2064-77. doi:10.1039/c4ob02459a