Publications – Theme 2 (AR. Gomes)
RECENT PUBLICATIONS
Ukegbu CV, Gomes AR, Giorgalli M, Campos M, Bailey AJ, Besson TRB, Billker O, Vlachou D, Christophides GK (2023) Identification of genes required for Plasmodium gametocyte-to-sporozoite development in the mosquito vector. Cell Host Microbe 31:1539-1551.e6. doi:10.1016/j.chom.2023.08.010
Gomes AR, Marin-Menendez A, Adjalley S, Bardy C, Cassan C, Lee M, et al (2022) A transcriptional switch controls sex determination in Plasmodium falciparum. Nature 612:528-533. doi:10.1038/s41586-022-05509-z
Ward D, Gomes AR, Tetteh K, Sepulveda N, Gomez LF, Campino S, Clark TG (2022) Sero-epidemiological study of arbovirus infection following the 2015–2016 Zika virus outbreak in Cabo Verde. Sci Rep 12:11719. doi:10.1038/s41598-022-16115-4
Gurung P, Gomes AR, Martins RM, Juranek SA, Alberti P, Mbang‐Benet D, et al (2021) PfGBP2 is a novel G‐quadruplex binding protein in Plasmodium falciparum. Cell Microbiol 23:e13303. doi:10.1111/cmi.13303
Campos M, Ward D, Morales RF, Gomes AR, Silva K, Sepúlveda N, et al (2020) Surveillance of Aedes aegypti populations in the city of Praia, Cape Verde: Zika virus infection, insecticide resistance and genetic diversity. Parasit Vectors 13:481. doi:10.1186/s13071-020-04356-z
Gazanion E, Lacroix L, Alberti P, Gurung P, Wein S, Mergny JL, Gomes AR* and Lopez-Rubio JJ* (2020) Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites. PLoS Genet 16:e1008917. doi:10.1371/journal.pgen.1008917. *Co-senior authorship
Benavente ED, Gomes AR, Silva JR, Grigg MJ, Walker H, Barber B, William T, Yeo TW, Sessions PF, Ramaprasad A, Ibrahim A, Charleston J, …, Campino SG, Clark T (2019) Whole genome sequencing of amplified Plasmodium knowlesi DNA from unprocessed blood reveals genomic exchange events between Malaysian Peninsular and Borneo subpopulations. Sci Rep 9(1):9873. doi:10.1038/s41598-019-46398-z
He Y, Campino SG, Benavente ED, Warhurst D, Beshir K, Lubis I, Gomes AR, Feng J, Jiazhi W, Sun X, Huang F, Tang L, Sutherland C, Clark T (2019) Artemisinin resistance-associated markers in Plasmodium falciparum parasites from the China-Myanmar border: predicted structural stability of K13 propeller variants detected in a low-prevalence area. PLoS One 14:e0213686 . doi:10.1371/journal.pone.0213686
Fang H*, Gomes AR*, Klages N*, Pino P, Maco B, Walker EM, Zenonos Z, Angrisano F, Baum J, Doerig C, Baker D, Billker O, Brochet M (2018) Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites. Nat Commun 9:4248. doi:10.1038/s41467-018-06733-w. *Co-first authorship
Reid AJ*, Talman AM*, Bennett HM*, Gomes AR, Sanders MJ, Illingworth CJR, Billker O, Berriman M, Lawniczak MKN (2018) Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites. eLife 7:e33105. doi:10.7554/eLife.33105
Gomes AR, Ravenhall M, Benavente ED, Talman A, Sutherland C, Roper C, Clark TG, Campino S (2017) Genetic diversity of next generation antimalarial targets: A baseline for drug resistance surveillance programmes. Int J Parasitol Drugs Drug Resist 7:174-180. doi:10.1016/j.ijpddr.2017.03.001
Mancio-Silva L, Slavic K, Grilo Ruivo MT, Grosso AR, Modrzynska KK, Vera IM, Sales-Dias J, Gomes AR, MacPherson CR, Crozet P, Adamo M, Baena-Gonzalez E, Tewari R, Llinás M, Billker O, Mota MM (2017) Nutrient sensing modulates malaria parasite virulence. Nature 547:213-216. doi:10.1038/nature2300
Modrzynska K, Pfander C, Chappell L, Yu L, Suarez C, Dundas K, Gomes AR, Goulding D, Rayner JC, Choudhary J, Billker O (2017) A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle. Cell Host Microbe 21:11-22. doi:10.1016/j.chom.2016.12.003
Dombrowski JG, Souza RM, Curry J, Hinton L, Silva NRM, Grignard L, Gonçalves LA, Gomes AR, Epiphanio S, Drakeley C, Huggett J, Clark TG, Campino S, Marinho CRF (2017) G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon. Malar J 16:253. doi:10.1186/s12936-017-1889-6
Bushell E*, Gomes AR*, Sanderson T*, Anar B, Girling G, Herd C, Metcalf T, Modrzynska K, Schwach F, Martin RE, Mather MW, McFadden GI, Parts L, Rutledge GG, Vaidya AB, Wengelnik K, Rayner JC, Billker O (2017) Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Cell 170, 260-272 e268. doi:10.1016/j.cell.2017.06.030. *Co-first authorship
Gomes AR, Talman AM (2016) Commitment issues in Plasmodium. Nat Rev Microbiol 14(1):4. doi:10.1038/nrmicro.2015.9
Gomes AR, Bushell E, Schwach F, Girling G, Anar B, Quail MA, Herd C, Pfander C, Modrzynska K, Rayner JC, Billker O (2015) A genome-scale vector resource enables high-throughput reverse genetic screening in a malaria parasite. Cell Host Microbe 17:404-13. doi:10.1016/j.chom.2015.01.014
Schwach F*, Bushell E*, Gomes AR, Anar B, Girling G, Herd C, Rayner JC, Billker O. “PlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites”. Nucleic Acids Res (2015) Jan;43: D1176-82.