Publications – Group A. Blanc-Potard

Press Releases

CNRS Biologie (2025): https://www.insb.cnrs.fr/fr/cnrsinfo/infection-chronique-ou-se-cachent-les-bacteries-pour-resister-aux-antibiotiques

CNRS Biologie (2019): https://insb.cnrs.fr/fr/cnrsinfo/tuer-avant-detre-tue-comment-une-bacterie-pathogene-resiste-au-macrophage

SELECTED Recent publications

Costes F, Nilly F, Rousset A, Pont S, Moreau K, Blanc-Potard AB. Modeling Pseudomonas aeruginosa–Staphylococcus aureus interactions in zebrafish to assess the host inflmamatory response upon co-infection. Sci Rep. 2025 15(1):23965. doi:10.1038/s41598-025-08459-4.

Pont S, Nilly F, Berry L, Bonhoure A, Alford MA, Louis M, Nogaret P, Lesouhaitier O, Hancock REW, Plésiat P, Blanc-Potard AB. Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model. PLoS Pathog. 2025 1:e1012922. doi:10.1371/journal.ppat.10129

Hajjar H, Berry L, Wu Y, Touqui L, Vergunst AC, Blanc-Potard AB. Contribution of intramacrophage stages to Pseudomonas aeruginosa infection outcome in zebrafish embryos: insights from mgtC and oprF mutants. Sci Rep. 2024. 14:6297. doi:10.1038/s41598-024-56725-8

Leiba J, Sipka T, Begon-Pescia C, Bernardello M, Tairi S, Bossi L, Gonzalez AA, Mialhe X, Gualda E, Loza-Alvarez P, Blanc-Potard A, Lutfalla G, Nguyen-Chi M (2024) Dynamics of macrophage polarization support Salmonella persistence in a whole living organism. Elife 13:e89828. doi:10.7554/eLife.89828

Rahimova R, Nogaret P, Huteau V, Gelin M, Clément DA, Labesse G, Pochet S*, Blanc-Potard AB*, Lionne C*. Structure-based design, synthesis and biological evaluation of a NAD⁺ analogue targeting Pseudomonas aeruginosa NAD kinase.FEBS J. 2023. 290:482-501. doi:10.1111/febs.16604

Moussouni M, Berry L,Sipka T, Nguyen-Chi M, Blanc-Potard AB. Pseudomonas aeruginosa OprF plays a role in resistance to macrophage clearance during acute infection. Sci Rep. 2021. 11, 359. doi:10.1038/s41598-020-79678-0

Pont S, Blanc-Potard AB. Zebrafish Embryo Infection Model to Investigate Pseudomonas aeruginosa Interaction With Innate Immunity and Validate New Therapeutics. Front Cell Infect Microbiol.2021. 11:745851. doi:10.3389/fcimb.2021.745851

Nogaret P, El Garah F, Blanc-Potard AB. A Novel Infection Protocol in Zebrafish Embryo to Assess Pseudomonas aeruginosa Virulence and Validate Efficacy of a Quorum Sensing Inhibitor In Vivo. Pathogens. 2021. 10(4):401. doi:10.3390/pathogens10040401

Garai P and Blanc-Potard AB. Uncovering small membrane proteins in pathogenic bacteria: regulatory functions and therapeutic potential. Mol. Microbiol.2020. 114:710-720. doi:10.1111/mmi.14564

Garai P, Berry L, Moussouni M, Bleves S, Blanc-Potard AB. Killing from the inside: Intracellular role of T3SS in the fate of Pseudomonas aeruginosa within macrophages revealed by mgtC and oprF mutants. PLOS Pathogens. 2019. 15(6): e1007812. doi.org/10.1371/journal.ppat.1007812

Moussouni M, Nogaret P, Garai P, Ize B, Vives E and Blanc-Potard AB. Activity of a synthetic peptide targeting MgtC on Pseudomonas aeruginosa intramacrophage survival and biofilm formation. Front. Cell. Infect. Microbiol. 2019. doi.org/10.3389/fcimb.2019.00084