Publications - Groupe M. Nguyen Chi

Publications récentes

Park SA, Lupi G, Ozbilgic R, Kollar M, Ozvat AA, Nguyen-Chi M, Mikula K (2026) Le paysage morpho-cinétique des modes de macrophages pendant la cicatrisation des plaies chez le poisson-zèbre. Sci Rep. Sous presse.

Begon-Pescia C, Manchon L, Özbilgiç R, Boireau S, Louis A, Georges S, Nguyen-Chi M (2026) Dynamique temporelle des profils transcriptionnels des macrophages pendant la cicatrisation des plaies chez le poisson-zèbre. Front Immunol 16:1721612. doi:10.3389/fimmu.2025.1721612

Lupi G, Park SA, Ambroz M, Ozbilgic R, Nguyen Chi M, Lutfalla G, Mikula K (2025) Méthodes mathématiques et numériques pour comprendre le mouvement des cellules immunitaires pendant la cicatrisation des plaies. Math Model Nat Phenom 20:28. doi:10.1051/mmnp/2025030

Begon-Pescia C, Özbilgiç R, Boireau S, Louis A, Georges S, Manchon L, Nguyen-Chi M (2025) Dynamique temporelle des profils transcriptionnels des macrophages pendant la cicatrisation des plaies chez le poisson-zèbre. bioRxiv 2025.09.12.675595. doi:10.1101/2025.09.12.675595

Park S A, Lupi G, Ozbilgic R, Kollar M, Ozvat A A, Nguyen-Chi M, Mikula K (2025) Le paysage morpho-cinétique des modes de macrophages pendant la cicatrisation des plaies chez le poisson-zèbre. arXiv:2507.19314. doi:10.48550/arXiv.2507.19314

van Dijk K S E, Begon-Pescia C, de Bruin B A, Özbilgiç R, Elks P M, Nguyen-Chi M, Forlenza M (2025) Lors d'une réponse inflammatoire, les gènes tnfa et tnfb du poisson-zèbre sont exprimés par différents types de cellules et présentent des cinétiques d'expression distinctes. bioRxiv2025.11.04.686030.doi:10.1101/2025.11.04.686030

Hernandez L, Paris T, Demou M, Birck C, Begon-Pescia C, Rodriguez-Vidal JF, Tyrkalska SD, Bureau C, Gonzalez C, Gracia J, Lelievre E, Mulero V, Nguyen-Chi M, Yatime L (2025) Les ictacalcines spécifiques aux téléostéens présentent une organisation structurelle, une activation dépendante des cations et une régulation transcriptionnelle similaires à celles des protéines S100 humaines.FEBS Jsous presse.doi:10.1111/febs.70354

Rivault A, Bernut A, Ben-Neji M, Abrantes M, Jansen M, Huc-Brandt S, Besteiro S, Bordat Y, Nguyen-Chi M, Audemard N, Mesleard-Roux M, Perrais D, Neyrolles O, Lugo-Villarino G, Vérollet C, Espert L, Beaumelle B (2025) HIV-1 Tat favorise la multiplication de Mycobacterium tuberculosis et Toxoplasma en inhibant l'endocytose médiée par la clathrine et l'autophagie. PLoS Pathog 21 : e1013183. doi:10.1371/journal.ppat.1013183

Pedoto A, Lozano Gil JM, Nguyen-Chi M, Lutfalla G, García-Moreno D, Mulero V, Tyrkalska SD (2025) Macrophage Inflammasome Activation Drives Anti-inflammatory Responses via Neutrophil-Derived ASC Speck Transfer and Gasdermin-Dependent Caspase-1 Inhibition. bioRxiv 2025.01.22.634381. doi:10.1101/2025.01.22.634381

Hernandez L, Paris T, Demou M, Birck C, Begon-Pescia C, Rodriguez-Vidal JF, Tyrkalska SD, Bureau C, Gonzalez C, Gracia J, Lelievre E, Mulero V, Nguyen-Chi M, Yatime L (2025) Teleost-specific ictacalcins exhibit similar structural organization, cation-dependent activation and transcriptional regulation as human S100 proteins. bioRxiv 2025.06.10.658860. doi:10.1101/2025.06.10.658860

Leiba J, Sipka T, Begon-Pescia C, Bernardello M, Tairi S, Bossi L, Gonzalez AA, Mialhe X, Gualda E, Loza-Alvarez P, Blanc-Potard A, Lutfalla G, Nguyen-Chi M (2024) Dynamics of macrophage polarization support Salmonella persistence in a whole living organism. Elife 13:e89828. doi:10.7554/eLife.89828

Resseguier J, Nguyen-Chi M, Wohlmann J, Rigaudeau D, Salinas I, Oehlers SH, Wiegertjes GF, Johansen FE, Qiao SW, Koppang EO, Verrier B, Boudinot P, Griffiths G (2023) Identification of a pharyngeal mucosal lymphoid organ in zebrafish and other teleosts : Tonsils in fish ? Sci Adv 9:eadj0101. doi:10.1126/sciadv.adj0101

Park SA, Sipka T, Kriva Z, Lutfalla G, Nguyen-Chi M, Mikula K (2023) Segmentation-based tracking of macrophages in 2D+time microscopy movies inside a living animal. Comput Biol Med 153, 106499. doi:10.1016/j.compbiomed.2022.106499

Leiba J, Ozbilgic R, Hernandez L, Demou M, Lutfalla G, Yatime L, Nguyen Chi M (2023) Molecular actors of inflammation and their signaling pathways : mechanistic insights from zebrafish. Biology 12, 153. doi : 10.3390/biology12020153

Sipka T, Park SA, Ozbilgic R, Balas L, Durand T, Mikula K, Lutfalla G, Nguyen-Chi M (2022) Macrophages undergo a behavioural switch during wound healing in zebrafish. Free Rad Biol Med 192:200-212. doi:10.1016/j.freeradbiomed.2022.09.021

Charmantier G, Nguyen-Chi M, Lutfalla G (2022) Ontogenetic Changes in Blood Osmolality During the Postembryonic Development of Zebrafish(Danio rerio). Zebrafish 19:1-6. doi:10.1089/zeb.2021.0075

Begon-Pescia C, Boireau S, Boyer-Clavel M, Lutfalla G, Nguyen-Chi M (2022) Preparing sequencing grade RNAs from a small number of FACS-sorted larvae macrophages isolated from enzyme free dissociated zebrafish larvae. MethodsX 9, 101651. doi:10.1016/j.mex.2022.101651

Sipka T, Peroceschi R, Hassan-Abdi R, Groß M, Ellett F, Begon-Pescia C, Gonzalez C, Lutfalla G, Nguyen-Chi M (2021) Damage-Induced Calcium Signaling and Reactive Oxygen Species Mediate Macrophage Activation in Zebrafish. Front Immunol 12:636585. doi:10.3389/fimmu.2021.636585

Laplace-Builhé B, Barthelaix A, Assou S, Bohaud C, Pratlong M, Severac D, Tejedor G, Luz-Crawford P, Nguyen-Chi M, Mathieu M, Jorgensen C, Djouad F (2021) NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration. Nat Commun 12:6336. doi:10.1038/s41467-021-26422-5

Jacobs S, Dóró E, Hammond FR, Scheer M, Nguyen-Chi M, Lutfalla L, Wiegertjes G, Forlenza M (2021) Occurrence of foamy macrophages during the innate response of zebrafish to trypanosome infections. eLife 10:e64520. doi:10.7554/eLife.64520

Travnickova J, Nhim S, Abdellaoui N, Djouad F, Nguyen-Chi M, Parmeggiani A, Kissa K (2021) Macrophage morphological plasticity and migration is Rac signalling and MMP9 dependant. Sci Rep 11, 10123. doi:10.1038/s41598-021-88961-7

Moussouni M, Berry L, Sipka T, Nguyen-Chi M, Blanc-Potard AB (2021) Pseudomonas aeruginosa OprF joue un rôle dans la résistance à la clairance des macrophages pendant l'infection aiguë. Sci Rep 11, 359. doi : 0.1038/s41598-020-79678-0

Nguyen-Chi M, Luz-Crawford P, Balas L, Sipka T, Contreras-López R, Barthelaix A, Lutfalla G, Durand T, Jorgensen C, Djouad F (2020) Pro-resolving mediator protectin D1 promotes epimorphic regeneration by controlling immune cell function in vertebrates. Br J Pharmacol 177, 4055-4073. doi:10.1111/bph.15156

Park SA, Sipka T, Krivá Z, Ambroz M, Kollár M, Kósa B, Nguyen-Chi M, Lutfalla G, Mikula K (2020) Macrophage Image Segmentation by Thresholding and Subjective Surface Method. Tatra Mt Math Publ 75, 103-120. doi:10.2478/tmmp-2020-0007

Travnickova J, Nhim S, Abdellaoui N, Djouad F, Nguyen-Chi M, Parmeggiani A, Kissa K. (2019) Macrophage plasticity is Rac signalling and MMP9 dependant. Preprint BioRxiv. doi:10.1101/614388

Phan QT, Sipka T, Gonzalez C, Levraud JP, Lutfalla G, Nguyen-Chi M (2018) Neutrophils use superoxide to control bacterial infection at a distance. PLoS Pathog 14:e1007157. doi:10.1371/journal.ppat.1007157

Nguyen-Chi M, Laplace-Builhé B, Travnickova J, Luz-Crawford P, Tejedor G, Lutfalla G, Kissa K, Jorgensen C, Djouad F (2017). La signalisation TNF et les macrophages gouvernent la régénération des nageoires chez les larves de poisson zèbre. Cell Death Dis 8:e2979. doi:10.1038/cddis.2017.374

Bernut A, Nguyen-Chi M, Halloum I, Herrmann JL, Lutfalla G, Kremer L (2016) Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking. PLoS Pathog 12 : e1005986. doi:10.1371/journal.ppat.1005986

Faure E, Campana M, Cunderlik R, Drblikova O, Duloquin L, Keller R, Lombardot B, Melani C, Remesikova M, Rizzi B, Savy T, Recher G, Zanella C, Kollar J, Villoutreix P, Delile J, Affaticati P, Maury, B, Colin I, Desnoulez S, Nief JY, Calvat P, Lutfalla G, Suret P, Doursat R, Sarti A, Mikula K, Peyriéras N, Bourgine P (2016) A workflow to process 3D+time images of developing organisms and reconstruct their cell lineage. Nat Commun 7:8674. doi:10.1038/ncomms9674

Nguyen-Chi M, Laplace-Builhe B, Jorgensen C, Djouad F (2016) Deciphering the complexity of macrophage biology and function with the zebrafish model. Macrophage 3:e1260. doi:10.14800/Macrophage.1260

Nguyen-Chi M, Laplace-Builhe B, Travnickova J, Luz-Crawford P, Tejedor G, Phan QT, Duroux-Richard I, Levraud JP, Kissa K, Lutfalla G, Jorgensen C, Djouad F (2015) Identification of polarized macrophage subsets in zebrafish. eLife 4:e07288. doi:10.7554/eLife.07288

Nguyen-Chi M, Phan QT, Gonzalez C, Dubremetz JF, Levraud JP, et al. (2014) Transient infection of the zebrafish notochord with E. coli induces chronic inflammation. Dis Model Mech 7:871-882. doi:10.1242/dmm.014498