Publications – Team T. Hollin

RECENT PUBLICATIONS

Hollin, T., Chahine, Z., Abel, S., Banks, C., Pasaje, C. F. A., Lenz, T., Prudhomme, J., Ybanez, C. M., Abbaszadeh, A. S., Niles, J. C., Florens, L., & Le Roch, K. G. (2025). RAP proteins regulate apicoplast noncoding RNA processing in Plasmodium falciparum. Cell reports, 44(7), 115928. doi.org/10.1016/j.celrep.2025.115928

Chahine ZM, Gupta M, Lenz T, Hollin T, Abel S, Banks C, Saraf A, Prudhomme J, Bhanvadia S, Florens LA, Le Roch KG (2024) PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum. Elife 12:RP92499. doi:10.7554/eLife.92499

Hollin T, Abel S, Banks C, Hristov B, Prudhomme J, Hales K, Florens L, Stafford Noble W, Le Roch KG (2024) Proteome-Wide Identification of RNA-dependent proteins and an emerging role for RNAs in Plasmodium falciparum protein complexes. Nat Commun 15(1):1365. doi:10.1038/s41467-024-45519-1

Hollin T, Le Roch KG (2023) Sex determination and transmission: Leveraging genetic screens to reveal Plasmodium’s secrets. Cell Host Microbe 31(9):1430-1432. doi:10.1016/j.chom.2023.08.007

Batugedara G, Lu XM, Hristov B, Abel S, Chahine Z, Hollin T, Williams D, Wang T, Cort A, Lenz T, Thompson TA, Prudhomme J, Tripathi AK, Xu G, Cudini J, Dogga S, Lawniczak M, Noble WS, Sinnis P, Le Roch KG (2023) Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum. Nat Commun 14(1):5086. doi:10.1038/s41467-023-40883-w

Hollin T, Chahine Z, Le Roch KG (2023) Epigenetic Regulation and Chromatin Remodeling in Malaria Parasites. Annu Rev Microbiol 77:255-276. doi:10.1146/annurev-micro-032521-041554

Hollin T, Abel S, Falla A, Pasaje CFA, Bhatia A, Hur M, Kirkwood JS, Saraf A, Prudhomme J, De Souza A, Florens L, Niles JC, Le Roch KG (2022) Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum. Nat Commun 13(1):1275. doi:10.1038/s41467-022-28981-7

Hollin T, Abel S, Le Roch KG (2021) Genome-Wide Analysis of RNA-Protein Interactions in Plasmodium falciparum Using eCLIP-Seq. Methods Mol Biol 2369:139-164. doi:10.1007/978-1-0716-1681-9_9

Hollin T, Jaroszewski L, Stajich JE, Godzik A, Le Roch KG (2021) Identification and phylogenetic analysis of RNA binding domain abundant in apicomplexans or RAP proteins. Microb Genom 7(3):mgen000541. doi:10.1099/mgen.0.000541

Davis SZ, Hollin T, Lenz T, Le Roch KG (2021) Three-dimensional chromatin in infectious disease-A role for gene regulation and pathogenicity? PLoS Pathog 17(2):e1009207. doi:10.1371/journal.ppat.1009207

Hollin T, Le Roch KG (2020) From Genes to Transcripts, a Tightly Regulated Journey in Plasmodium. Front Cell Infect Microbiol 10:618454. doi:10.3389/fcimb.2020.618454

Hollin T, Gupta M, Lenz T, Le Roch KG (2021) Dynamic Chromatin Structure and Epigenetics Control the Fate of Malaria Parasites. Trends Genet 37(1):73-85. doi:10.1016/j.tig.2020.09.003