News – Team 6

March 2024

‘Article of the Month’ prize from SFBBM awarded to Theo Paris

Theo received this prize from SFBBM for his article on the IbeA virulence factor from adherent invasive E. coli.

Congratulations!

Link to the SFBBM website


March 2024

INFLANET meeting in Visegard, Hungary

The final INFLANET review meeting was held on March 23-24 in the beautiful city of Visegrad in Hungary.

The meeting was combined to the European Phagocyte Workshop and the satellite INFLANET Dissemination conference.

All our ESRs gave great talks at the meetings on their latest scientific results.

All the participants also enjoyed a well-deserved break with a medieval dinner at the Renaissance restaurant!


February 2024

Colloque Français des Jeunes Chercheurs VLM’ in Paris

Flore wins the ‘Best Talk’ award at the CFJC VLM 2024 in Paris. Congratulations!

Sarahdja and Floriane had also great talk and poster sessions.

Well done, girls!


January 2024

New publication in eLife journal by the group of M. Nguyen Chi

Illuminating the hiding place of Salmonella in living host – The group of Mai Nguyen Chi developed a new model of persistent infection in zebrafish allowing to visualize in live where Salmonella enterica establishes its niche to persist long-term in the host. This study showed that Salmonella persist in anti-inflammatory/ pro-regenerative motionless macrophages.

Link to the article


NOVEMBER 2023

PhD defense of Théo Paris

On November 27th, Théo Paris defended is PhD thesis entitled “Virulence mechanisms of adherent invasive Escherichia coli and antibacterial strategies in Crohn’s disease” and supervised by Dr. Laure Yatime.

The jury was composed of Dr. Laurent Terradot (MMSB, Lyon), Dr. Pierre Germon (INRAE, Tours), Dr. Elisabeth Billard (M2iSH, Clermont-Ferrand) and Dr. Pierre Boudinot (INRAE, Jouy-en-Josas).


NOVEMBER 2023

Novel lymphoid organ in the zebrafish, and other teleost fish

A collaborative study between groups from University of Oslo, INRAE, A*STAR, Wageningen University & Research, CNRS and the group of Mai Nguyen Chi identifies a new tonsil-like organ in fish which probably protect them from pathogens and suggests that the fish immune system is more sophisticated than previously thought.

The study was just published in Science Advances and made the cover of the November issue. It was also highlighted in a Commentary in Science.

Link to the article

Link to the commentary in Science


OCTOBER 2023

New publication in FEBS Journal about the IbeA virulence factor from AIEC by Paris et al

The group of Laure Yatime has elucidated the role of the IbeA protein, a virulence factor from the adherent invasive Escherichia coli (AIEC) strain involved in the pathogenesis of Crohn’s disease.

The biological function of this protein has long remained of debate. But this new study,conducted by PhD student Théo Paris, has allowed to demonstrate that IbeA function as a FAD-dependent oxidoreductase, thus permitting survival of the AIEC bacteria within the highly oxidative environment of the phagosomal compartments within host macrophages through the modulation of redox processes.

Link to the article


September 2023

Welcome to Floriane Costes who starts her PhD thesis in the lab!


July 2023

Congratulations to Anne Blanc-Potard who obtains an ANR PRC grant at the AAPG 2023!